Adsorbent media for liquid phase separations

用于液相分离的吸附介质

• 批准号: 1058373
• 负责人: Luis Colon
• 金额: $ 46.2万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1058373&HistoricalAwards=false
• 关键词: Adsorbent; media; liquid; phase; separations

Professor Luis A. Colon of SUNY at Buffalo is supported by the Chemical Measurement and Imaging (CMI) Program in the Division of Chemistry to develop chromatographic separation media based on detonation nanodiamond (ND) material. NDs with a uniform particle size of 4-5 nm will be linked to the surface of monodispersed silica solid supports. The physicochemical properties of the resulting ND-silica material will be investigated with a battery of instrumental analysis techniques, including IR spectroscopy, elemental analysis, gas adsorption analysis and ESCA. The adsorptive characteristics of these relatively unexplored chromatographic separation media will be evaluated for applications in high performance liquid chromatography (HPLC), capillary electrophoresis (CE) and capillary electrochromatography (CEC). There is a growing interest in the development of ND-based separation media because of the excellent chemical and thermal stability of NDs, which make them appealing from the stand point of chromatography. The proposed research will lead to efficient chromatographic ND-based separation media and will open up possibilities for their use in specific practical applications. HPLC, CE and CEC are indispensable analytical tools that facilitate advances in the chemical, biological, and relate sciences. The project will contribute to the education and training of graduate and undergraduate students, including members of traditionally underrepresented groups, in the synthesis and characterization of novel separation media and in chromatography and other analytical separations technologies.

Luis A.位于布法罗的纽约州立大学科隆分校得到了化学部化学测量和成像（CMI）计划的支持，以开发基于爆轰纳米金刚石（ND）材料的色谱分离介质。具有4-5 nm的均匀粒度的ND将连接到单分散二氧化硅固体载体的表面。所得ND-二氧化硅材料的物理化学性质将与仪器分析技术，包括红外光谱，元素分析，气体吸附分析和ESCA电池进行研究。这些相对未开发的色谱分离介质的吸附特性将被评估在高效液相色谱（HPLC），毛细管电泳（CE）和毛细管电色谱（CEC）的应用。由于ND优异的化学稳定性和热稳定性，从色谱的角度来看，它们具有吸引力，因此对基于ND的分离介质的开发越来越感兴趣。拟议的研究将导致有效的色谱ND为基础的分离介质，并将开辟其在特定的实际应用中使用的可能性。 HPLC、CE和CEC是促进化学、生物和相关科学进步的不可或缺的分析工具。该项目将有助于教育和培训研究生和本科生，包括传统上代表性不足的群体的成员，在合成和表征新的分离介质和色谱法和其他分析分离技术。