Acquisition of a Quadrupole Ion Trap Mass Spectrometer

收购四极离子阱质谱仪

• 批准号: 9709233
• 负责人: Peter Dervan
• 金额: $ 16.87万
• 依托单位: California Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 1998-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9709233&HistoricalAwards=false
• 关键词: Acquisition; Quadrupole; Ion; Trap; Mass

*** 9709233 DERVAN This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program will assist the Department of Chemistry at the California Institute of Technology to acquire a quadrupole ion trap mass spectrometer. This equipment will enhance research in a number of areas including the following: (1) long -range electron transfer (ET) reactions, (2) bimolecular and unimolecular reactions of peptides and oligonucleotides, and (3) application of metal-peptide complexes for the sequence-specific binding and reaction with double helical DNA. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to protein and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest technique available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry. ***

*** 9709233 DERVAN化学研究仪器和设施奖 （CRIF）计划将协助化学系在加州 技术研究所获得四极离子阱质量 光谱仪这一设备将加强若干领域的研究 包括：（1）长程电子转移（ET） 反应，（2）肽的双分子和单分子反应， 寡核苷酸，和（3）金属-肽络合物的应用 与双螺旋DNA的序列特异性结合和反应。 质谱（MS）是用于探测紧密结构的技术， 详细信息，并获得大量的分子组成， 有机、生物有机和有机金属分子。的加入 电喷雾技术将质谱的范围扩展到蛋白质和核酸 酸的分子量远远超过任何其他技术。使用 电喷雾电离结合高分辨率提供了 质谱分析的最新技术它为化学家提供了 一个最强大的工具，可用于表征 化合物.在质谱分析中获得这种能力是 对许多领域的前沿研究至关重要， 化学. ***