Designer Paths for Guided Axon Extension in Three- Dimensional Structures

9805835 Hu该项目的长期目标是开发一种在三维基质中引导神经轴突生长的方法，用于组织工程应用。为了促进生物活性分子在三维结构中的选择性沉积，将采用一种依靠穿透激光在空间上控制生物活性分子结合的光化学技术。这种方法可以应用于沉积几乎任何可以连接到PhotoLinker的分子。这个项目的直接目标是应用开发的方法来研究在二维表面和三维结构中寻找路径的关键因素。***

9805835 Hu The long-term objective of this project is to develop a method of directing nerve axonal growth within three-dimensional matrices for tissue engineering applications. To facilitate the selective deposition of biologically active molecules in a three-dimensional structure, a photochemical technique will be employed that relies on a penetrating laser to spatially control the binding of bioactive molecules. This method can be applied to deposit virtually any molecule that can be conjugated to a photolinker. The immediate objective of this project is to apply the developed method to investigate the factors critical to path finding in both two-dimensional surfaces and three-dimensional structures. ***