Three-dimensional finite element modelling of skeletal muscles: Parameter identification, simulation and verification

骨骼肌三维有限元建模:参数辨识、仿真与验证

基本信息

项目摘要

As most muscles are tightly packed in ‘muscle-packages’, they have to interact with surrounding muscle tissue during contraction. In order to gain a deeper understanding of muscle packing under the premise of force generation and contraction velocity, it is necessary to study the architecture, the three-dimensional deformation and the power development of muscle packages.Based on this question, the main goal of this project throughout the entire funding phase is the development of a three-dimensional muscle model that allows realistic predictions of force development and three-dimensional deformation during muscle contractions. This was already achieved for the soleus muscle (SOL) of the rabbit. In this final funding phase, the developed model will also be transferred to other calf muscles of the rabbit (gastrocnemius muscle: GAS, plantaris muscle: PLA), which will ultimately be merged into a muscle package model (SOL, GAS, PLA).Thus, the goal of this final phase, which completes the overall project, is the additional acquisition of geometry data (aponeurosis localisation, three-dimensional fibre distributions) whose necessity has been proven due to the impact of muscle packing on muscle architecture. Further, open work from the previous funding phase for the characterisation of the material properties of GAS and PLA as well as for data evaluation and model validation shall be completed. Due to time-consuming and sometimes unexpected working steps (which were necessary for the processing of the application), this was not possible in the previously funded project period. Hence, there are extensive, experimental, three-dimensional muscle surface data during contraction for the GAS and the entire muscle package that still need to be evaluated.The data collected in this last funding phase will be incorporated into a three-dimensional model describing the muscle package. Thus, for the first time, a muscle package model is available, which enables the handling of selected questions on the function and the design of muscles, muscle packages and body segments.
由于大多数肌肉都被“肌肉包装”紧密地包装,因此他们必须在合同期间与周围的肌肉组织相互作用。为了在力量产生和收缩速度的前提下更深入地了解肌肉堆积,有必要研究架构,三维变形和肌肉套件的功率发展。基于这个问题,该项目的主要目标是整个资金阶段的主要目标,是在三维肌肉模型中的开发,可以在工子发展和三维方面进行三维预测。这已经为兔子的比目鱼肌(Sol)实现了。 In this final funding phase, the developed model will also be transferred to other calf muscles of the rabbit (gastrocnemius muscle: GAS, plantaris muscle: PLA), which will ultimately be merged into a muscle package model (SOL, GAS, PLA).Thus, the goal of This final phase, which completes the overall project, is the additional acquisition of geometry data (aponeurosis localisation, three-dimensional fibre distributions) whose necessary由于肌肉包装对肌肉建筑的影响,已被证明。此外,应完成以上基础阶段的开放工作,以表征气体和PLA的材料特性以及数据评估和模型验证。由于时间耗时,有时甚至是意外的工作步骤(这对于应用程序的处理是必需的),因此在先前资助的项目期间不可能。因此,在收缩期间,气体和仍需要评估的整个肌肉包装有广泛的,实验性的三维肌肉表面数据。在最后一个融资阶段收集的数据将纳入描述肌肉包装的三维模型中。这是第一次提供肌肉包装模型,该模型可以处理有关肌肉,肌肉包装和身体段功能和设计的选定问题。

项目成果

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Professor Dr.-Ing. Markus Böl其他文献

Professor Dr.-Ing. Markus Böl的其他文献

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{{ truncateString('Professor Dr.-Ing. Markus Böl', 18)}}的其他基金

Thermo-mechanical de-icing
热机械除冰
  • 批准号:
    456102901
  • 财政年份:
    2021
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Development and validation of a constitutive growth model for brain tissue characterising brain alterations in space and time
开发和验证脑组织的本构生长模型,表征大脑在空间和时间上的变化
  • 批准号:
    404568779
  • 财政年份:
    2018
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Development of a three-dimensional model of structural and functional changes during skeletal muscle growth: Experiment, simulation and validation
骨骼肌生长过程中结构和功能变化的三维模型的开发:实验、模拟和验证
  • 批准号:
    316485047
  • 财政年份:
    2018
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Experimental analysis and mathematical modelling of mechano-regulated growth and remodelling processes in urinary bladders of post-pubescent pigs
青春期后猪膀胱机械调节生长和重塑过程的实验分析和数学建模
  • 批准号:
    386349077
  • 财政年份:
    2018
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Cleaning mechanisms of immerged systems
浸入式系统的清洁机制
  • 批准号:
    326771530
  • 财政年份:
    2017
  • 资助金额:
    --
  • 项目类别:
    Research Grants
The role of meso-scale structure on the mechanical response of soft musculoskeletal tissues
细观结构对软肌肉骨骼组织机械响应的作用
  • 批准号:
    320032210
  • 财政年份:
    2017
  • 资助金额:
    --
  • 项目类别:
    Research Grants
From muscle fibre to tissue - experiment, modelling and simulation at micro, meso and makro scale
从肌肉纤维到组织 - 微观、中观和宏观尺度的实验、建模和模拟
  • 批准号:
    258667461
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Biofilmmechanik - Numerische und experimentelle Untersuchung der mechanischen Beanspruchung von Biofilmsystemen
生物膜力学 - 生物膜系统机械应力的数值和实验研究
  • 批准号:
    182156884
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
    Research Grants
Entwicklung einer mikromechanisch basierten Modellierung zur Finite-Elemente-Simulation des physiologischen Verhaltens von Skelettmuskeln
开发基于微机械的模型,用于骨骼肌生理行为的有限元模拟
  • 批准号:
    43700770
  • 财政年份:
    2007
  • 资助金额:
    --
  • 项目类别:
    Research Grants
CISM-Kurs "Biomechanical modelling at the molecular, cellular and tissue levels" (11.-15.09.2006 in Udine/Italien)
CISM 课程“分子、细胞和组织水平的生物力学建模”(2006 年 9 月 11 日至 15 日,意大利乌迪内)
  • 批准号:
    32684308
  • 财政年份:
    2006
  • 资助金额:
    --
  • 项目类别:
    Research Grants

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