A Cell Culture Core Facility and Equipment for InvestigativeExperiments in Cell Biology for the Undergraduate Curriculum

本科生课程细胞生物学研究实验的细胞培养核心设施和设备

• 批准号: 9850614
• 负责人: Christopher Gillen
• 金额: $ 3.69万
• 依托单位: Kenyon College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9850614&HistoricalAwards=false
• 关键词: Cell; Culture; Core; Facility; Equipment

Undergraduate exposure to modern methods in cell biology is crucial to a sound biological or biochemical education because of the central, integrative role that cellular studies play in modern bioscience. At present, important aspects of modern cellular studies are missing from our laboratory curriculum. We propose to remedy this by the purchase of equipment that would allow the addition of investigation-based labs that utilize cell culture, substantively improving courses in the biology and chemistry departments at both the introductory and advanced levels. Many fascinating phenomena are readily approached using cells grown in vitro, and innovative lab additions will afford students new opportunities to conduct experiments in exciting areas of current cell biology, including investigations of dynamic processes in live cells. These activities will furnish striking insights into various cellular mechanisms, and will kindle student awareness of the relevance of cellular studies to diverse disciplines. This should lead more students to consider career paths in cellular bioscience. In addition to use in formal laboratory classes, proposed equipment will see further student use in honors research, independent research during the academic year, and summer research. This project will thus allow us to fill important gaps in our curriculum, and also to broaden the scope of undergraduate research at Kenyon. The project will be implemented by a team of four faculty from the biology and chemistry departments. We plan thorough evaluation of new labs and extensive dissemination of successful experiments through print and electronic media. In a novel use of student-generated data, we will with ongoing student involvement, create online notebooks that will allow any individual with WWW access to conduct investigations that mimic our students' experiences. We expect that our dissemination efforts will not only lead to emulation of some of our labs, but will stimulate remote, virtual investigations of exciting cellular phenomena. Hence, this project has potential to furnish widely-used improvements in biology education.

本科生接触现代方法细胞生物学是一个健全的生物或生化教育的关键，因为中央，综合作用，细胞研究在现代生物科学中发挥。目前，我们的实验室课程中缺少现代细胞研究的重要方面。我们建议通过购买设备来弥补这一点，这些设备将允许增加利用细胞培养的基于调查的实验室，从而大大改善生物和化学系的入门和高级课程。许多迷人的现象很容易接近使用体外培养的细胞，创新的实验室增加将为学生提供新的机会，在当前细胞生物学的令人兴奋的领域进行实验，包括活细胞中的动态过程的调查。这些活动将提供各种细胞机制的深刻见解，并将点燃学生对细胞研究与不同学科相关性的认识。这应该会让更多的学生考虑细胞生物科学的职业道路。除了在正式的实验室课程中使用外，建议的设备将进一步用于学生的荣誉研究，学年期间的独立研究和夏季研究。因此，这个项目将使我们能够填补我们的课程的重要空白，并扩大在凯尼恩本科研究的范围。该项目将由来自生物和化学系的四名教师组成的团队实施。我们计划对新实验室进行全面评估，并通过印刷和电子媒体广泛传播成功的实验。在学生生成的数据的新用途，我们将与持续的学生参与，创建在线笔记本，将允许任何个人与WWW访问进行调查，模仿我们的学生的经验。我们希望我们的传播工作不仅会导致我们的一些实验室的模仿，但将刺激远程，令人兴奋的细胞现象的虚拟调查。因此，该项目有潜力提供广泛使用的生物教育的改进。