Molecule Liftoff from Surfaces

分子从表面剥离

• 批准号: 0071686
• 负责人: Barbara Garrison
• 金额: $ 50.04万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-05-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0071686&HistoricalAwards=false
• 关键词: Molecule; Liftoff; Surfaces

The research program entitled "Molecule Liftoff from Surfaces" will be performed by Dr. Barbara Garrison of Pennsylvania State University and is supported by the Analytical and Surface Chemistry program. This computational research program will focus on modeling the behavior of solid organic surfaces under impact by fast particles or during laser ablation. These basic calculations will provide a fundamental framework which will lead to a better understanding of analytical techniques such as Secondary Ion Mass Spectrometry (SIMS) and Matrix Assisted Laser Desorption Ionization Mass Spectrometry (MALDI). The calculations are based on experimental data provided by collaborators which is a significant component of this project. The goals of the project include developing simulations to better understand the desorption of large organic molecules from surfaces, the enhanced desorption efficiency when using polyatomic projectiles, and the experimentally observed differences between UV-MALDI and IR-MALDI.The analytical techniques of SIMS and MALDI have applications in biochemistry, surface chemistry, polymer chemistry and many others. They are widely used techniques in the pharmaceutical industry, electronics industry, and chemical industry. The fundamental research to be performed in this project will lead to improved interpretation of the data obtained and more effective use of these techniques in problem solving applications.

这项名为“表面分子剥离”的研究计划将由宾夕法尼亚州立大学的Barbara Garrison博士执行，并得到分析和表面化学计划的支持。 这个计算研究计划将专注于模拟固体有机表面在快速粒子冲击下或激光烧蚀过程中的行为。 这些基本计算将提供一个基本框架，这将导致更好地理解分析技术，如二次离子质谱（西姆斯）和基质辅助激光解吸电离质谱（MALDI）。 计算是基于合作者提供的实验数据，这是该项目的重要组成部分。 该项目的目标包括开发模拟，以更好地了解大的有机分子从表面的解吸，增强解吸效率时，使用多原子射弹，和UV-MALDI和IR-MALDI之间的实验观察到的差异。西姆斯和MALDI的分析技术在生物化学，表面化学，高分子化学和许多其他应用。 它们在制药工业、电子工业和化学工业中被广泛使用。 在这个项目中进行的基础研究将导致所获得的数据的更好的解释和更有效地使用这些技术在解决问题的应用。