Acquisition of an Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometer for Research and Education

采购用于研究和教育的电喷雾电离四极杆飞行时间质谱仪

• 批准号: 0091718
• 负责人: Fred Hawkridge
• 金额: $ 18.68万
• 依托单位: Virginia Commonwealth University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-02-15 至 2004-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0091718&HistoricalAwards=false
• 关键词: Acquisition; Electrospray; Ionization; Quadrupole; Time

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Virginia Commonwealth University will acquire an Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometer. This equipment will enhance research in a number of areas including a) electron transfer reactions between cytochrome c, cytochrome c oxidase and dioxygen; b) characterization of chemical dynamics in complex systems; c) biomimetic-supported catalysts for oxygen- and peroxide-dependent oxidations; d) assessment of antibody-based sensors for trace analysis of environmental contaminants; e) lanthanide(III) macrocyclic complexes as luminescent bio-markers; and f) resonance Raman of oxidized peroxidases. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The results from these studies will have an impact in a number of areas including environmental chemistry and biochemistry.

凭借化学研究仪器和设施 (CRIF) 计划的这一奖项，弗吉尼亚联邦大学化学系将获得一台电喷雾电离四极杆飞行时间质谱仪。该设备将加强多个领域的研究，包括a）细胞色素c、细胞色素c氧化酶和双氧之间的电子转移反应； b) 复杂系统中化学动力学的表征； c) 用于氧和过氧化物依赖性氧化的仿生负载催化剂； d) 评估用于环境污染物痕量分析的基于抗体的传感器； e) 镧系元素(III)大环配合物作为发光生物标记物； f) 氧化过氧化物酶的共振拉曼。 质谱 (MS) 是一种用于探测密切结构细节并获取大量有机、生物有机和有机金属分子的分子组成的技术。这些研究的结果将对包括环境化学和生物化学在内的许多领域产生影响。