MRI: Acquisition of a Liquid Chromatography Electrospray Ionization (LC-ESI) Mass Spectrometer for Undergraduate Research

MRI：为本科生研究购买液相色谱电喷雾电离 (LC-ESI) 质谱仪

• 批准号: 1039259
• 负责人: Jody Modarelli
• 金额: $ 39.9万
• 依托单位: Hiram College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-15 至 2013-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1039259&HistoricalAwards=false
• 关键词: MRI; Acquisition; Liquid; Chromatography; Electrospray

This Major Research Instrumentation award funds the acquisition of a Liquid Chromatography Electrospray Ionization Mass Spectrometer (LC ESI-MS) at Hiram College. The new LCMS system provides a unique way to elucidate the structure of molecules in complex experiments, and will help faculty at Hiram College to identify fatty acids in biological samples (plasma & insects), detect secondary plant metabolites, analyze large chlorinated compounds, and differentiate metabolic profiles of wild-type and mutant Xenopus. The research projects at Hiram College are at the forefront of their respective fields and will be used as a training ground for undergraduates both in classroom courses and independent research projects. The LCMS will be used as part of a collaborative program at Hiram College, "Research in the Classroom," that allows students to experience real world research problems as part of their coursework. Such an approach fosters independent thought within each student in the classroom as they conduct their research in the field or in the lab. Results from the studies conducted with the LCMS will be broadly disseminated through abstracts and peer reviewed publications, as well as by active participation of students and faculty at professional meetings.

该主要研究仪器奖资助希拉姆学院购买液相色谱电喷雾电离质谱仪（LC ESI-MS）。新的LCMS系统提供了一种独特的方式来阐明复杂实验中的分子结构，并将帮助希拉姆学院的教师识别生物样品（血浆昆虫）中的脂肪酸，检测次生植物代谢产物，分析大型氯化化合物，并区分野生型和突变型非洲爪蟾的代谢谱。 希拉姆学院的研究项目处于各自领域的前沿，将作为本科生课堂课程和独立研究项目的培训基地。 LCMS将被用作希拉姆学院“课堂研究”合作项目的一部分，该项目允许学生体验真实的世界研究问题，作为他们课程的一部分。 这种方法培养了每个学生在课堂上的独立思考，因为他们在现场或实验室进行研究。 从与LCMS进行的研究结果将通过摘要和同行评议的出版物，以及学生和教师在专业会议的积极参与广泛传播。