MRI: Acquisition of a Liquid Chromatography Electrospray Ionization (LC-ESI) Mass Spectrometer for Undergraduate Research

这一重大研究仪器奖用于资助希拉姆学院购买高效电喷雾电离质谱仪(LC ESI-MS)。新的LC MS系统提供了一种在复杂实验中阐明分子结构的独特方法，并将帮助希拉姆学院的教员识别生物样本(血浆和昆虫)中的脂肪酸，检测次生植物代谢物，分析大型氯化化合物，并区分野生型和突变型非洲爪哇的代谢特征。西拉姆学院的研究项目处于各自领域的前沿，将作为本科生在课堂课程和独立研究项目中的培训基地。该课程将作为希拉姆学院一个名为“课堂研究”的合作项目的一部分，让学生在课程中体验现实世界中的研究问题。这种方法培养了课堂上每个学生在实地或实验室进行研究时的独立思维。研究结果将通过摘要和同行评议出版物，以及学生和教职员工积极参加专业会议的方式广泛传播。

This Major Research Instrumentation award funds the acquisition of a Liquid Chromatography Electrospray Ionization Mass Spectrometer (LC ESI-MS) at Hiram College. The new LCMS system provides a unique way to elucidate the structure of molecules in complex experiments, and will help faculty at Hiram College to identify fatty acids in biological samples (plasma & insects), detect secondary plant metabolites, analyze large chlorinated compounds, and differentiate metabolic profiles of wild-type and mutant Xenopus. The research projects at Hiram College are at the forefront of their respective fields and will be used as a training ground for undergraduates both in classroom courses and independent research projects. The LCMS will be used as part of a collaborative program at Hiram College, "Research in the Classroom," that allows students to experience real world research problems as part of their coursework. Such an approach fosters independent thought within each student in the classroom as they conduct their research in the field or in the lab. Results from the studies conducted with the LCMS will be broadly disseminated through abstracts and peer reviewed publications, as well as by active participation of students and faculty at professional meetings.