Synthetic Methods Based on Nickel Metallacycles

基于镍金属环的合成方法

• 批准号: 0093048
• 负责人: John Montgomery
• 金额: $ 33万
• 依托单位: Wayne State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2005-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0093048&HistoricalAwards=false
• 关键词: Synthetic; Methods; Based; Nickel; Metallacycles

The Synthetic Organic Program is awarding a grant to John Montgomery at the Department of Chemistry, Wayne State University. This grant will continue his research into asymmetric nickel-catalyzed cyclizations. Mechanistic studies and the development of new catalytic, enantioselective processes will be pursued. The preparation of a number of (poly)cycles to illustrate the utility of the methodology will be carried out.Professor Montgomery's research provides an excellent training ground for students in organic and organometallic chemistry. These students then enter the pharmaceutical and chemical workforce, as well as academia. This research into nickel-catalyzed cyclizations to form new cyclic compounds is most likely to find applications in the preparation of pharmaceutical agents.

合成有机计划将向州立大学州立大学韦恩化学系的约翰蒙哥马利提供资助。 这项资助将继续他对不对称镍催化环化反应的研究。 将进行机理研究和开发新的催化、对映选择性过程。 将准备一些（聚）循环来说明该方法的实用性。蒙哥马利教授的研究为有机和有机金属化学的学生提供了一个良好的训练基地。 这些学生然后进入制药和化学劳动力，以及学术界。 镍催化环化反应形成新的环状化合物的研究最有可能在药物制剂的制备中找到应用。