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Synthetic Methods Based on Nickel Metallacycles

Synthetic Methods Based on Nickel Metallacycles
基于镍金属环的合成方法
批准号:
0093048
负责人:
John Montgomery
金额:
$33.0万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-03-01 至 2005-02-28

项目摘要

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中文摘要
翻译
合成有机项目授予韦恩州立大学化学系的约翰·蒙哥马利一笔资助。这笔资助将继续他对镍催化的不对称环化反应的研究。机理研究和新的催化,对映选择性过程的发展将继续进行。一些(多)周期的准备,以说明该方法的效用将进行。蒙哥马利教授的研究为学生在有机和有机金属化学方面提供了一个很好的训练基地。这些学生随后进入制药和化学行业,以及学术界。镍催化环化反应形成新的环状化合物的研究最有可能在药物制剂的制备中找到应用。
英文摘要
The Synthetic Organic Program is awarding a grant to John Montgomery at the Department of Chemistry, Wayne State University. This grant will continue his research into asymmetric nickel-catalyzed cyclizations. Mechanistic studies and the development of new catalytic, enantioselective processes will be pursued. The preparation of a number of (poly)cycles to illustrate the utility of the methodology will be carried out.Professor Montgomery's research provides an excellent training ground for students in organic and organometallic chemistry. These students then enter the pharmaceutical and chemical workforce, as well as academia. This research into nickel-catalyzed cyclizations to form new cyclic compounds is most likely to find applications in the preparation of pharmaceutical agents.
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会议论文
CAS: New Strategies for Sustainable Methods in Nickel-Catalyzed Coupling Reactions
SusCHEM: Development of New Reductive Transformations Utilizing First-Row Metal Catalysis
SusChEM: New Strategies for Catalytic Couplings, Cycloadditions, and Redox Conversions
Redox Control of Transition Metal Catalyzed Processes
国内基金
海外基金
Computational Methods for Analyzing Toponome Data