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Synthetic Methods Based on Nickel Metallacycles

Synthetic Methods Based on Nickel Metallacycles
基于镍金属环的合成方法
批准号:
0093048
负责人:
John Montgomery
金额:
$33.0万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-03-01 至 2005-02-28

项目摘要

项目成果

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中文摘要
翻译
合成有机项目向韦恩州立大学化学系的约翰·蒙哥马利颁发了一笔赠款。这笔赠款将继续他对不对称镍催化环化反应的研究。将继续进行机理研究和开发新的催化、对映体选择性工艺。将进行一些(聚)循环的准备,以说明该方法的实用性。蒙哥马利教授的研究为学生在有机和有机金属化学方面提供了一个很好的培训基础。然后,这些学生进入制药和化工劳动力市场,以及学术界。这项关于镍催化的环化反应形成新的环状化合物的研究最有可能在药物制剂的制备中找到应用。
英文摘要
The Synthetic Organic Program is awarding a grant to John Montgomery at the Department of Chemistry, Wayne State University. This grant will continue his research into asymmetric nickel-catalyzed cyclizations. Mechanistic studies and the development of new catalytic, enantioselective processes will be pursued. The preparation of a number of (poly)cycles to illustrate the utility of the methodology will be carried out.Professor Montgomery's research provides an excellent training ground for students in organic and organometallic chemistry. These students then enter the pharmaceutical and chemical workforce, as well as academia. This research into nickel-catalyzed cyclizations to form new cyclic compounds is most likely to find applications in the preparation of pharmaceutical agents.
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会议论文
CAS: New Strategies for Sustainable Methods in Nickel-Catalyzed Coupling Reactions
SusCHEM: Development of New Reductive Transformations Utilizing First-Row Metal Catalysis
SusChEM: New Strategies for Catalytic Couplings, Cycloadditions, and Redox Conversions
Redox Control of Transition Metal Catalyzed Processes
国内基金
海外基金
Computational Methods for Analyzing Toponome Data