Conference: Post-transcriptional Control of Gene Expression in Plants to be held May 10-13, 2001 at the Iowa State Univ., Ames, IA

0104911 W.艾伦米勒基因表达的重要调控发生在许多水平后，转录的遗传信息到信使RNA。 本次会议将重点关注RNA调控的机制，从核中的转录直到编码的遗传信息通过翻译转化为蛋白质。 直到最近，转录后事件，如mRNA加工，mRNA降解和翻译还没有在植物中得到广泛的研究。 然而，令人兴奋的新发现揭示了大量的转录后控制事件，从细微的（例如，mRNA稳定性）到崇高（例如，转录后基因沉默）。 全体发言人将涵盖不同的生物功能，如宿主-病原体相互作用，非生物胁迫反应，叶绿体功能和植物发育。 将涵盖以下具体主题：RNA介导的转录后基因沉默;抑制基因沉默; mRNA周转;前mRNA剪接;新型病毒mRNA翻译机制;植物基因的翻译控制;生物信息学和基因组学。 本次会议的与会者将加深对基因表达机制惊人多样性的认识。 此外，这次会议将强调需要进一步研究了解基因表达的转录后调控，因为更多的真核生物基因组即将完成，新的基因被发现。

0104911 W. Allen MillerSignificant regulation of gene expression occurs at many levels after transcription of genetic information into messenger RNA. This meeting will focus on mechanisms of RNA regulation, from transcription in the nucleus until the encoded genetic information has been converted to protein via translation. Until recently, post-transcriptional events, such as mRNA processing, mRNA decay, and translation have not been studied extensively in plants. However, exciting new discoveries have revealed a plethora of post-transcriptional control events ranging from the subtle (e.g., mRNA stability) to the sublime (e.g., post-transcriptional gene silencing). The plenary speakers will cover diverse biological functions such as host-pathogen interactions, abiotic stress response, chloroplast function, and plant development. The following specific topics will be covered: RNA-mediated, post-transcriptional gene silencing; suppression of gene silencing; mRNA turnover; pre-mRNA splicing; novel viral mRNA translation mechanisms; translational control of plant genes; and bioinformatics and genomics. Attendees of this meeting will come away with an increased awareness of the amazing diversity of gene expression mechanisms. Furthermore, this meeting will highlight the need for further research into understanding post-transcriptional regulation of gene expression as more eukaryotic genomes are nearing completion and new genes are discovered.