Conference: Post-transcriptional Control of Gene Expression in Plants to be held May 10-13, 2001 at the Iowa State Univ., Ames, IA

会议：植物基因表达的转录后控制将于 2001 年 5 月 10-13 日在爱荷华州立大学（爱荷华州艾姆斯）举行

• 批准号: 0104911
• 负责人: Wyatt Miller
• 金额: $ 1.75万
• 依托单位: Iowa State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0104911&HistoricalAwards=false
• 关键词: Conference; Post; transcriptional; Control; Gene

0104911 W. Allen MillerSignificant regulation of gene expression occurs at many levels after transcription of genetic information into messenger RNA. This meeting will focus on mechanisms of RNA regulation, from transcription in the nucleus until the encoded genetic information has been converted to protein via translation. Until recently, post-transcriptional events, such as mRNA processing, mRNA decay, and translation have not been studied extensively in plants. However, exciting new discoveries have revealed a plethora of post-transcriptional control events ranging from the subtle (e.g., mRNA stability) to the sublime (e.g., post-transcriptional gene silencing). The plenary speakers will cover diverse biological functions such as host-pathogen interactions, abiotic stress response, chloroplast function, and plant development. The following specific topics will be covered: RNA-mediated, post-transcriptional gene silencing; suppression of gene silencing; mRNA turnover; pre-mRNA splicing; novel viral mRNA translation mechanisms; translational control of plant genes; and bioinformatics and genomics. Attendees of this meeting will come away with an increased awareness of the amazing diversity of gene expression mechanisms. Furthermore, this meeting will highlight the need for further research into understanding post-transcriptional regulation of gene expression as more eukaryotic genomes are nearing completion and new genes are discovered.

0104911 W. Allen Miller在遗传信息转录成信使RNA后，基因表达的显着调节发生在许多水平上。 本次会议将重点讨论 RNA 调控机制，从细胞核中的转录到编码的遗传信息通过翻译转化为蛋白质。 直到最近，转录后事件（例如 mRNA 加工、mRNA 衰减和翻译）尚未在植物中得到广泛研究。 然而，令人兴奋的新发现揭示了大量的转录后控制事件，从微妙的（例如，mRNA 稳定性）到崇高的（例如，转录后基因沉默）。 全体会议发言人将涵盖多种生物功能，例如宿主与病原体的相互作用、非生物胁迫反应、叶绿体功能和植物发育。 将涵盖以下具体主题：RNA介导的转录后基因沉默；抑制基因沉默； mRNA周转；前mRNA剪接；新型病毒 mRNA 翻译机制；植物基因的翻译控制；以及生物信息学和基因组学。 这次会议的与会者将更加认识到基因表达机制的惊人多样性。 此外，随着更多真核基因组接近完成和新基因的发现，本次会议将强调需要进一步研究了解基因表达的转录后调控。