Incorporation of GC/MS into the Undergraduate Analytical Chemistry Curriculum

化学(12)芝加哥洛约拉大学正在将三个利用GC/MS作为主要成分的实验室实验整合到本科分析实验室课程中。化学专业的定量分析课程使用电子俘获电离(ECI)和GC/MS相结合的方法，在飞秒/皮克水平上对模型芳香胺--苯胺进行定量。新开设的环境化学课程的本科生正在分析水样中低水平的氯代酚。仪器分析实验室的学生正在比较基于GC/MS的铅测定方法与电感耦合等离子体质谱(ICPMS)和其他分析方法。这些实验是从研究和教育文献中改编和实施的，强调与处理和提取少量分析物有关的技能的发展。分析化学专业的学生开始熟悉GC/MS检测和定量极少量(飞克级)分析物的能力，特别是通过使用电子捕获作为GC/MS的电离技术。一旦学生熟悉GC/MS，他们将把他们的知识应用于实际样品的分析，包括密歇根湖的水和芝加哥地区住房项目的油漆碎片。

Chemistry (12)Loyola University of Chicago is integrating three laboratory experiments that are utilizing GC/MS as the principal component into the undergraduate analytical laboratory curriculum. Chemistry majors in the Quantitative Analysis course are using electron capture ionization (ECI) in conjunction with GC/MS to quantify a model aromatic amine, aniline, at the femtogram/picogram level. Undergraduates in the newly-established Environmental Chemistry course are analyzing low levels of chlorinated phenols in watersamples. Students in the Instrumental Analysis laboratory are comparing a GC/MS-based method for the determination of lead to inductively-coupled plasma (ICP) mass spectrometry and other analytical methods. The experiments have been adapted and implemented from the research and educational literature and are emphasizing the development of skills associated with handling and extracting small quantities of analyte. Analytical chemistry students are becoming acquainted with the power of GC/MS to detect and quantify very small (femtogram level) amounts of analyte, particularly through the use of electron capture as the ionization technique for GC/MS. Once the students are familiar with the GC/MS, they are applying their knowledge to the analysis of real-world samples, including water from Lake Michigan and paint chips from housing projects in the Chicago area.