US-Germany Cooperative Research: Stochastic Phase Resetting in Oscillatory Neurons

美德合作研究：振荡神经元的随机相位重置

• 批准号: 0233264
• 负责人: David Russell
• 金额: $ 1.78万
• 依托单位: University of Missouri-Saint Louis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-02-01 至 2006-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0233264&HistoricalAwards=false
• 关键词: US; Germany; Cooperative; Research; Stochastic

0233264NeimanThis award supports the PI, co-PI, and graduate students from the University of Missouri-St. Louis in a collaboration with Peter Tass of the Institute for Medicines at the Research Center Juelich, Germany. The joint research effort will combine theoretical and experimental studies of mechanisms of stochastic synchronization and de-synchronization for deep brain stimulation therapy of Parkinson's disease by the German group and experimental electrophysiological and theoretical modeling of stochastic synchronization and phase resetting in electroreceptors of paddlefish by the US group. The specific goal of the collaboration is to understand general mechanisms for controlling synchronization in noisy oscillating neurons and to validate the effectiveness and neural basis of novel stimulus protocols developed by the German group for treating Parkinson's patients by deep brain stimulation.The project also has an educational objective. The project will allow the graduate students involved to benefit from performing research in another country. They will develop a heightened appreciation of the world around them while also learning important new technical skills.

0233264 Neiman该奖项支持PI，共同PI和密苏里大学圣路易斯分校的研究生与德国Juelich研究中心药物研究所的Peter塔斯合作。 联合研究工作将结合联合收割机的理论和实验研究的随机同步和去同步机制的脑深部刺激治疗帕金森病和实验电生理和理论建模的随机同步和相位重置的白鲟的电感受器的美国组。 该合作的具体目标是了解控制噪声振荡神经元同步的一般机制，并验证德国研究小组开发的用于治疗帕金森氏症患者的脑深部电刺激新刺激方案的有效性和神经基础。该项目还具有教育目的。 该项目将使参与的研究生能够从在另一个国家进行研究中受益。 他们将提高对周围世界的欣赏力，同时也学习重要的新技术技能。