NUE: Engineering Properties and Micro/Nano Technologies for Biological Systems

这个纳米技术在本科教育（NUE）奖亚利桑那大学支持博士Eniko T。航空航天和机械工程系的Enikov和农业和生物系统工程系的Joel Cuello博士，他们的工作是开发一套本科实验室实验，重点是生物传感器的纳米尺度表面科学。BioMEMS和生物传感器由于其在从生物技术和医学诊断到环境监测和生物战的广泛应用中的潜在用途而引起了极大的兴趣。大多数生物传感器的关键组成部分是能够识别特定分析物分子的人工表面。 这项工作将扩大新开发的跨学科本科课程“生物系统的工程特性和微/纳米技术”，通过开发五个实验，以支持生物活性表面纳米工程的讲座课程。具体而言，实验将集中在微悬臂梁探针的制造，有机单层（SAMs）的自组装，SAMs的微接触印刷，通过纳米压痕测量生物膜的弹性特性，以及用微悬臂梁传感器测量自组装单分子膜的表面应力。拟议的实验室发展是一个多部门总体计划的一部分，该计划旨在建立一个学院，关于微型和纳米技术的广泛本科课程不仅满足本科工程专业学生的需求，而且满足其他科学专业学生的需求，如生物科学，光学和物理学。它的设计使命是激励广泛的学生在纳米技术领域从事科学事业。该奖项的建议是响应纳米科学和工程教育公告，NSF 03-044，类别NUE，并由土木和机械系统（CMS）和生物工程和环境系统（BES）在工程局（ENG）和生物科学局（BIO）的部门共同资助。

This Nanotechnology in Undergraduate Education (NUE) award to the University of Arizona supports Dr. Eniko T. Enikov, Department of Aerospace and Mechanical Engineering, and Dr. Joel Cuello, Agricultural and Biosystems Engineering for their work to develop a set of undergraduate laboratory experiments that are focused on the nano-scale surface science of biosensors. BioMEMS and biosensors have generated significant interest because of their potential use in a wide spectrum of applications ranging from biotechnology and medical diagnostics to environmental monitoring and biological warfare. The key component of most biosensors is an artificial surface capable of recognizing a specific analyte molecule. This effort will expand the newly developed interdisciplinary undergraduate course "Engineering Properties and Micro/Nano Technologies for Biological Systems" through the development of five experiments in support of a lecture-based course on the nanoengineering of biologically active surfaces. Specifically, the experiments will focus on fabrication of micro-cantilever probes, self-assembly of organic monolayers (SAMs), micro-contact printing of SAMs, measurements of elastic properties of bio-films via nano-indentation, and measurement of the surface stress of self-assembled monolayers with micro-cantilever sensors.The proposed laboratory development is part of a multi-departmental master plan for the creation of a college-wide undergraduate curriculum on micro- and nano-technologies addressing the needs not only of undergraduate engineering students but also of students from other sciences, such as biosciences, optics, and physics. It is being designed with the mission of inspiring a broad spectrum of students to pursue scientific careers in the area of nanotechnology. The proposal for this award was received in response to the Nanoscale Science and Engineering Education announcement, NSF 03-044, category NUE and was jointly funded by the Division of Civil and Mechanical Systems (CMS) and the Division of Bioengineering and Environmental Systems (BES) in the Directorate for Engineering (ENG) and the Directorate for Biological Sciences (BIO).