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Biophotonics: Dynamical Cellular Imaging by Compact Arrays of Blue and Ultraviolet Light Emitting Diodes

Biophotonics: Dynamical Cellular Imaging by Compact Arrays of Blue and Ultraviolet Light Emitting Diodes
生物光子学:通过蓝色和紫外发光二极管紧凑阵列进行动态细胞成像
批准号:
0423566
负责人:
Arto Nurmikko
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2004
资助国家:
美国
项目状态:
已结题
起止时间:
2004-09-01 至 2008-05-31

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中文摘要
翻译
该研究将适应和推进紧凑型宽禁带半导体光发射器件(led)在短波长的应用,用于生物材料/系统的成像。特别是,他们将设计、制造和定制蓝色和紫色led,使其成为多功能多元素阵列,通过基于荧光的激发,在芯片上实现神经细胞网络动态的实时成像。此外,紫外led将被用于以时空选择性的方式赋予这种细胞网络光化学激发,以实现神经电路和人造光电子电路之间的交互接口。
英文摘要
0423566NurmikkoThe proposed research will adapt and advance compact wide bandgap semiconductor light emitter devices (LEDs) at short wavelengths for their application to imaging of biological materials/systems. In particular, they will design, fabricate, and tailor blue and violet LEDs into versatile multi-element arrays that will enable the real-time imaging of the dynamics of neural cell networks via fluorescence-based excitation, on-chip. Further, ultraviolet LEDs will be employed to impart photochemical excitation of such cellular networks in a spatio-temporally selective manner for the goal of implementing an interactive interface between neural circuits and man-made optoelectronic circuits.
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An Optoelectronics Device to Write-In and Read-Out Activity in Brain Circuits
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