Biophotonics: Dynamical Cellular Imaging by Compact Arrays of Blue and Ultraviolet Light Emitting Diodes

生物光子学：通过蓝色和紫外发光二极管紧凑阵列进行动态细胞成像

• 批准号: 0423566
• 负责人: Arto Nurmikko
• 金额: --
• 依托单位: Brown University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0423566&HistoricalAwards=false
• 关键词: Biophotonics; Dynamical; Cellular; Imaging; Compact

0423566NurmikkoThe proposed research will adapt and advance compact wide bandgap semiconductor light emitter devices (LEDs) at short wavelengths for their application to imaging of biological materials/systems. In particular, they will design, fabricate, and tailor blue and violet LEDs into versatile multi-element arrays that will enable the real-time imaging of the dynamics of neural cell networks via fluorescence-based excitation, on-chip. Further, ultraviolet LEDs will be employed to impart photochemical excitation of such cellular networks in a spatio-temporally selective manner for the goal of implementing an interactive interface between neural circuits and man-made optoelectronic circuits.

0423566Nurmikko 拟议的研究将适应和推进短波长的紧凑型宽带隙半导体发光器件（LED），以应用于生物材料/系统的成像。特别是，他们将设计、制造蓝色和紫色 LED 并将其定制为多功能多元件阵列，从而能够通过片上基于荧光的激发对神经细胞网络的动态进行实时成像。此外，紫外LED将用于以时空选择性方式对此类细胞网络进行光化学激发，以实现神经电路和人造光电电路之间的交互接口。