Acquisition of an Upgrade for a 500 MHz NMR Spectrometer

获得 500 MHz NMR 波谱仪的升级版

• 批准号: 0614785
• 负责人: Fraser Fleming
• 金额: $ 38.38万
• 依托单位: Duquesne University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-15 至 2009-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0614785&HistoricalAwards=false
• 关键词: Acquisition; Upgrade; 500; MHz; NMR

With support from the Major Research Instrumentation (MRI) Acquisition Program, the Department of Chemistry and Biochemistry at Duquesne University will upgrade a 500 MHz NMR spectrometer. The upgraded spectrometer will foster conceptually new research on nitrile anions, transition metal catalysis, anti-tumor agents, emerging drug targets, reactive molybdenum intermediates and elucidate protein-nucleic acid interactions. Nuclear Magnetic Resonance (NMR) Spectroscopy is the most widely used tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances and to provide information on the arrangement and connectivity of atoms in molecules. Dynamical information is obtained providing insight on the motions of molecules. This award will provide essential analytical capabilities to faculty and students at Duquesne University and be used occasionally by several other smaller institutions that have collaborations with Duquesne.

在主要研究仪器（MRI）获取计划的支持下，迪肯大学化学与生物化学系将升级一台500 MHz核磁共振光谱仪。升级后的光谱仪将促进对腈阴离子、过渡金属催化、抗肿瘤药物、新兴药物靶点、活性钼中间体和阐明蛋白质与核酸相互作用的概念性新研究。核磁共振（NMR）波谱是化学家用于分子结构分析的最广泛使用的工具。它用于识别未知物质，并提供有关分子中原子的排列和连通性的信息。获得的动力学信息提供了对分子运动的深入了解。该奖项将为杜肯大学的教师和学生提供必要的分析能力，并偶尔被与杜肯大学合作的其他几所较小的机构使用。