Acquisition of an Upgrade for a 500 MHz NMR Spectrometer

在重大研究仪器(MRI)采购计划的支持下，迪奎恩大学化学和生物化学系将升级一台500 MHz核磁共振光谱仪。升级后的光谱仪将在概念上促进对氰基阴离子、过渡金属催化、抗肿瘤药物、新兴药物靶标、活性钼中间体的研究，并阐明蛋白质与核酸的相互作用。核磁共振波谱是化学家用于阐明分子结构的最广泛使用的工具。它被用来识别未知物质，并提供有关分子中原子的排列和连接性的信息。获得的动力学信息提供了对分子运动的洞察。该奖项将为杜肯大学的教职员工和学生提供基本的分析能力，并偶尔被与杜肯大学有合作关系的其他几个较小的机构使用。

With support from the Major Research Instrumentation (MRI) Acquisition Program, the Department of Chemistry and Biochemistry at Duquesne University will upgrade a 500 MHz NMR spectrometer. The upgraded spectrometer will foster conceptually new research on nitrile anions, transition metal catalysis, anti-tumor agents, emerging drug targets, reactive molybdenum intermediates and elucidate protein-nucleic acid interactions. Nuclear Magnetic Resonance (NMR) Spectroscopy is the most widely used tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances and to provide information on the arrangement and connectivity of atoms in molecules. Dynamical information is obtained providing insight on the motions of molecules. This award will provide essential analytical capabilities to faculty and students at Duquesne University and be used occasionally by several other smaller institutions that have collaborations with Duquesne.