Investigating Membrane Proteins with Magnetic Resonance Spectroscopy

用磁共振波谱研究膜蛋白

• 批准号: 0645709
• 负责人: Gary Lorigan
• 金额: $ 39万
• 依托单位: Miami University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-15 至 2011-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0645709&HistoricalAwards=false
• 关键词: Investigating; Membrane; Proteins; Magnetic; Resonance

In this award, funded by the Experimental Physical Chemistry Program of the Chemistry Division, Prof. Gary A. Lorigan of Miami University of Ohio and his postdoctoral graduate and undergraduate student colleagues will use EPR spectroscopy to study the structural and dynamic properties of membrane-bound proteins. The information from these studies will help to understand how these ubiquitous proteins function under physiological conditions.Besides the broader scientific impact of the research, Prof. Lorigan will specifically target undergraduate students from groups traditionally underrepresented in the sciences for inclusion in his research group during the summer. He will do this through working with his Departmental NSF-REU Program, the University Hughes Program, and through the PI's informal contacts with Central State University.

在这个由化学学部实验物理化学项目资助的奖项中，俄亥俄迈阿密大学的Gary A. Lorigan教授和他的博士后和本科生同事将使用EPR光谱研究膜结合蛋白的结构和动态特性。这些研究的信息将有助于了解这些无处不在的蛋白质在生理条件下的功能。除了研究的更广泛的科学影响外，Lorigan教授还将专门针对传统上在科学领域代表性不足的群体的本科生，在夏季将其纳入他的研究小组。他将通过他的部门NSF-REU项目、大学休斯项目以及PI与中央州立大学的非正式联系来完成这项工作。