Evaporation Assisted Plasma Lithography for Biomimetic Proteins

仿生蛋白质的蒸发辅助等离子体光刻

• 批准号: 0855890
• 负责人: Pak Kin Wong
• 金额: $ 35.18万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0855890&HistoricalAwards=false
• 关键词: Evaporation; Assisted; Plasma; Lithography; Biomimetic

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). Many proteins in nature, such as silk and elastin, have superior physical properties. Inspired by the superior properties of these proteins, the goal of this project is to investigate an Evaporation-Assisted Plasma Lithography process for assembling biomimetic protein structures. The parameters that control the assembly process will be studied systematically. The assembled biomimetic protein structures will be investigated by different characterization techniques. The proposed work will lead to a novel nanomanufacturing strategy for biomimetic proteins, and will provide the foundation for utilizing the potential of biomimetic proteins in numerous engineering and biomedical applications in the future. This study will impact the manufacturing processes of many biomimetic proteins and nanoscale building blocks. The combination of the unique characteristics of biomimetic proteins and the innovative nanomanufacturing technique will open up new possibilities in creating hybrid microsystems by integrating bottom-up created building blocks and top-down fabricated micro and nano platforms. The proposed process will form the foundation for a new class of smart microdevices with broad applicability in manufacturing, bioengineering, and materials science. In addition, the visualization nature of guided manufacturing of nanostructures could provide appealing demonstrations to interest a diverse group of students and the general public. The research activity will be integrated into different education and outreach activities including graduate and undergraduate courses, undergraduate research experiences, and outreach and minority programs.

该奖项根据 2009 年美国复苏和再投资法案（公法 111-5）提供资金。 自然界中的许多蛋白质，如丝和弹性蛋白，都具有优越的物理性质。 受到这些蛋白质卓越特性的启发，该项目的目标是研究用于组装仿生蛋白质结构的蒸发辅助等离子体光刻工艺。 将系统地研究控制装配过程的参数。 组装的仿生蛋白质结构将通过不同的表征技术进行研究。 拟议的工作将为仿生蛋白质带来一种新颖的纳米制造策略，并为未来在众多工程和生物医学应用中利用仿生蛋白质的潜力奠定基础。 这项研究将影响许多仿生蛋白质和纳米级构建模块的制造过程。 仿生蛋白质的独特特性与创新的纳米制造技术的结合将为通过集成自下而上创建的构建块和自上而下制造的微米和纳米平台来创建混合微系统开辟新的可能性。 所提出的工艺将为新型智能微型设备奠定基础，在制造、生物工程和材料科学领域具有广泛的适用性。 此外，纳米结构引导制造的可视化性质可以提供有吸引力的演示，以吸引不同群体的学生和公众的兴趣。 研究活动将融入不同的教育和外展活动，包括研究生和本科生课程、本科生研究经验以及外展和少数群体项目。