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Engineering peptides into superglues selective for target proteins

Engineering peptides into superglues selective for target proteins
将肽工程化为对目标蛋白具有选择性的强力胶
批准号:
DP160104442
负责人:
Prof David Fairlie
金额:
$37.48万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31

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中文摘要
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英文摘要
This project aims to discover how to create long-acting peptides for future research tools, drugs, biosensors and diagnostics. Peptides are currently viewed by the general community as injectable performance-enhancing drugs which are difficult to detect because they don't last very long. However, peptides have many potential benefits that are difficult to obtain because of their short durations of action. This project aims to develop ways of engineering peptide shapes into nanoscale superglues that stick more tightly but selectively to their target proteins, thereby extending their durations of action. Technology for engineering superglues would produce proof of concept and prototypes for future research tools, drugs, diagnostics and biosensors.
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