Acquisition of a 400 MHz NMR Spectrometer for Chemical Research and Learning

根据化学研究仪器和设施：部门多用户仪器项目（CRIF:MU）授予的这份合同，威斯康星大学麦迪逊分校的Robert Hamers教授及其同事将获得一台400 MHz核磁共振光谱仪。此次收购将推进以下研究领域的研究：(a)生物活性物质的合成，(b)肽折叠体的合成和构象，(c)碳水化合物衍生物的化学合成，(d)二氮磷烷和催化不对称合成，(e)有机分子选择性有氧氧化的催化方法，以及(f)对映选择性c - h键氧化。核磁共振（NMR）波谱是化学家鉴别未知物质、跟踪化学反应过程、阐明分子结构以及研究固体和溶液中分子间相互作用动力学的有力工具。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在开展前沿研究和培养学生在现代研究技术。这些核磁共振研究的结果将对威斯康星大学的合成有机和无机化学研究产生影响。它将用于培养学生在本科实验课程。该仪器将提供给威斯康星州系统中其他本科院校的用户。

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multi-User Instrumentation program (CRIF:MU), Professor Robert Hamers and colleagues from the University of Wisconsin Madison will acquire a a 400 MHz NMR spectrometer. The acquisition will advance research in areas of study such as (a) synthesis of bioactive substances, (b) synthesis and conformations of peptidic foldamers, (c) chemical synthesis of carbohydrate derivatives, (d) diazaphospholanes and catalytic asymmetric synthesis, (e) catalytic methods for selective aerobic oxidation of organic molecules, and (f) enantioselective C-H bond oxidation.Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful tool used by chemists to identify unknown substances, to follow the progress of chemical reactions, to elucidate molecular structures, and to study the dynamics of interactions between molecules in solids and in solution. Access to state-of-the-art NMR spectrometers is essential for chemists who are carrying out frontier research and training students in modern research techniques. The results from these NMR studies will have an impact in synthetic organic and inorganic chemistry research at the University of Wisconsin. It will be used to train students in undergraduate laboratory courses. The instrument will be available to users at other undergraduate institutions in the Wisconsin system.