Studies of Deep Cavity Cavitands

深腔空穴体的研究

• 批准号: 1052806
• 负责人: Bruce Gibb
• 金额: $ 40.2万
• 依托单位: University of New Orleans
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2012-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1052806&HistoricalAwards=false
• 关键词: Studies; Deep; Cavity; Cavitands

Professor Bruce Gibb at the University of New Orleans is supported by the Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division to study the supramolecular chemistry of self-assembling systems in aqueous solution and to devise chemically complex systems possessing unusual properties. The first aim of this project is to investigate new separation protocols that utilize selective molecular encapsulation. In these systems, supramolecular structures encapsulate selected targets of complex chemical mixtures, isolating them from the bulk reactive environment. The second aim is to devise multi-(supra)molecular systems that evolve to equilibrium slowly and demonstrate unusual relationships between the components and the net overall state of the system. The third aim focuses on understanding supramolecular chemistry in the fluorous phaseThe proposed studies investigate the properties of nano-sized capsules that are formed in water. The capsules trap other molecules within their interior and, much like familiar capsules for drug formulations, engender a physical separation between what is within the capsule and what lies outside. At the molecular level this separation leads to many unusual phenomena, two of which are being investigated in this program of study. They are: 1) New ways to bring about the separation of chemicals that cannot be separated by current technologies, with impact in areas such as biological and dietary science; 2) Complex chemical systems whose overall properties are greater than the sum of their parts. Complex systems demonstrate emergence, or properties and phenomena that only arise through synergism. Life-forms are considered complex systems, and the proposed studies will aid in disentangling the complex intertwining of different processes. The research project will offer a stimulating research environment for the education and training of students, including members of the underrepresented groups.

新奥尔良大学的布鲁斯·吉布（Bruce Gibb）教授得到了化学部的大分子，超分子和纳米化学计划的支持，以研究水溶液中自组装系统的超分子化学，以设计具有异常特性的化学复杂系统。该项目的第一个目的是研究利用选择性分子封装的新分离方案。在这些系统中，超分子结构封装了复杂化学混合物的选定靶标，将它们与大量反应性环境隔离。第二个目的是设计多（上线）分子系统，该系统发展为缓慢的平衡，并表现出组件与系统净状态之间的异常关系。第三个目的是理解荧光素化学研究中的超分子化学研究，研究了水中形成的纳米尺寸胶囊的性质。胶囊将其他分子捕获在其内部内部，就像药物配方的熟悉胶囊一样，在胶囊内的物体和外部所处的东西之间进行了物理分离。在分子水平上，这种分离导致许多异常现象，其中两个正在研究中。它们是：1）实现无法通过当前技术分离的化学物质分离的新方法，并在生物学和饮食科学等领域产生影响； 2）复杂的化学系统的整体性质大于其部分的总和。复杂的系统表明出现，或仅通过协同作用而产生的特性和现象。生命形式被认为是复杂的系统，拟议的研究将有助于解散不同过程的复杂交织。该研究项目将为学生（包括代表性不足的群体的成员）提供刺激的研究环境。