MRI: Acquisition of a Liquid Chromatograph-Mass Spectrometer to Support Student/Faculty Research and Research Training

MRI：购买液相色谱-质谱仪以支持学生/教师的研究和研究培训

• 批准号: 1624377
• 负责人: David Blauch
• 金额: $ 29.99万
• 依托单位: Davidson College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1624377&HistoricalAwards=false
• 关键词: MRI; Acquisition; Liquid; Chromatograph; Mass

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor David Blauch from Davidson College and colleagues Durwin Striplin, Cindy Hauser and Nicole Snyder have acquired a liquid chromatograph mass spectrometer (LCMS) equipped with electrospray-ionization (ESI) and atmospheric pressure chemical ionization (APCI) sources coupled to the liquid chromatograph. Mass spectrometry (MS) is an analytical technique used to identify the chemical composition of a sample and to determine its purity by measuring the mass of the molecular constituents in the sample. Chromatography is an isolation technique that precedes the mass spectrometry analysis. It separates a mixture of components in a liquid into its several constituent chemicals which are then analyzed and identified by the mass spectrometer. The electrospray produces an aerosol of ions by applying a high voltage to the sample. These are some of the most widely used analytical instrumentation techniques used to identify and quantify the chemical composition of a sample. The acquisition strengthens the research infrastructure at the University and regional area. The instrument broadens participation by involving diverse students in research and research training with this modern analytical technique and also and also supports research efforts from two other local universities, Queens University of Charlotte, a masters-level regional university, and Johnson C. Smith University, an HBCU.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) developing chromophores and redox assemblies for solar energy conversion; (b) synthesizing and profiling complex carbohydrate constructs with proteins and other biomolecules; and (c) examining the reactivity of non-innocent ligand-metal complexes.

在主要研究仪器计划（MRI）的这一奖项和化学研究仪器计划（CRIF）的支持下，戴维森学院的大卫布劳赫教授及其同事Durwin Striplin，Cindy豪瑟和Nicole Snyder获得了一台液相色谱质谱仪（LCMS），该质谱仪配备了电喷雾电离（ESI）和大气压化学电离（APCI）源，并与液相色谱仪耦合。质谱法（MS）是一种分析技术，用于鉴定样品的化学成分，并通过测量样品中分子成分的质量来确定其纯度。色谱法是一种先于质谱分析的分离技术。它将液体中成分的混合物分离成几种化学成分，然后由质谱仪进行分析和鉴定。 电喷雾通过向样品施加高电压来产生离子气溶胶。这些是一些最广泛使用的分析仪器技术，用于识别和量化样品的化学成分。此次收购加强了大学和地区的研究基础设施。该仪器通过让不同的学生参与研究和研究培训来扩大参与，并使用这种现代分析技术，还支持其他两所当地大学的研究工作，即夏洛特皇后大学（一所硕士级地区大学）和约翰逊C。该奖项旨在加强各级研究和教育，特别是在以下领域：（a）开发用于太阳能转换的发色团和氧化还原组件;（B）合成和分析具有蛋白质和其他生物分子的复杂碳水化合物结构;（c）检查非无辜配体-金属络合物的反应性。