EAGER: Minimally invasive biosensors for detecting flavivirus infection

EAGER：用于检测黄病毒感染的微创生物传感器

• 批准号: 1651359
• 负责人: Roger Narayan
• 金额: $ 8万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2019-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1651359&HistoricalAwards=false
• 关键词: EAGER; Minimally; invasive; biosensors; detecting

AbstractPublic health experts are concerned that Zika virus may soon be spread by mosquitoes in the continental United States. The goal of this project is to understand if patches that contain small nozzles (known as "microneedles") can detect infection by Zika virus. This technology may allow healthcare providers to improve management and treatment of patients who present with Zika-like symptoms. This project involves creating electrodes that can detect components of the Zika virus. These electrodes will be combined with microneedles to create inexpensive, painless, and portable patches. The program will examine the functionality of the microneedle-containing patches with Zika component-containing blood and skin.

公共卫生专家担心寨卡病毒可能很快就会通过蚊子在美国大陆传播。该项目的目标是了解含有小喷嘴的贴片(称为微针)是否可以检测到寨卡病毒的感染。这项技术可能会让医疗保健提供者改善对出现寨卡病毒样症状的患者的管理和治疗。该项目涉及制造能够检测寨卡病毒成分的电极。这些电极将与微针相结合，创造出廉价、无痛和便携的贴片。该计划将检查含有微针的贴片与含有寨卡病毒成分的血液和皮肤的功能。

项目成果

Analytical methods for detection of Zika virus

寨卡病毒检测的分析方法

• DOI: 10.1557/mrc.2017.20
• 发表时间: 2017
• 期刊: MRS Communications
• 影响因子: 1.9
• 作者: Yang, Kai-Hung;Narayan, Roger J.
• 通讯作者: Narayan, Roger J.

Two-photon polymerization for biological applications

• DOI: 10.1016/j.mattod.2017.06.004
• 发表时间: 2017-07-01
• 期刊: MATERIALS TODAY
• 影响因子: 24.2
• 作者: Nguyen, Alexander K.;Narayan, Roger J.
• 通讯作者: Narayan, Roger J.

Polyethylenimine-mediated synthetic insertion of gold nanoparticles into mesoporous silica nanoparticles for drug loading and biocatalysis

• DOI: 10.1116/1.4979200
• 发表时间: 2017-03-01
• 期刊: BIOINTERPHASES
• 影响因子: 2.1
• 作者: Pandey, Prem C.;Pandey, Govind;Narayan, Roger J.
• 通讯作者: Narayan, Roger J.