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SNM: Additive Nanomanufacturing of Integrated Systems for Customized Personal Health Monitoring

SNM：用于定制个人健康监测的集成系统的增材纳米制造

基本信息

批准号：
1727918
负责人：
Neil Dasgupta
金额：
$ 150万
依托单位：
Regents of the University of Michigan - Ann Arbor
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-01 至 2022-08-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1727918&HistoricalAwards=false
关键词：
SNM Additive Nanomanufacturing Integrated Systems

项目摘要

In today's economy of planned obsolescence, most consumer electronics can only be customized at the software level. In contrast, hardware that is specific to the user is out of economic reach for the vast majority of the world's population. Therefore, one of the key manufacturing challenges of the 21st century is the sustainable, energy-efficient, and cost-effective customizable production of systems that are personalized to each individual. This need is especially acute in the medical arena, in which personalized health monitoring requires integrated systems that are customized to the unique physiological composition and the geometric form of the individual. This Scalable NanoManufacturing (SNM) research project explores the surface chemistry and physical processes needed to directly print three-dimensional integrated systems with nanoscale features, and strategies to monitor and assure quality control of the printed materials and structures. These techniques can be used to realize three-dimensional customized systems such as smart contact lenses, which would enable a paradigm shift in continuous and non-invasive health monitoring by integrating sensors that can detect chemical changes in the body with wireless communication and power to transmit data to the user. This research combines several disciplines including nanomanufacturing, modeling and simulation, process control, system integration, and in situ characterization. The societal impact of the work is through public education workshops, outreach programs, and a new university course on advanced nanomanufacturing.Current nanomanufacturing research has focused on high-volume, high-throughput techniques to produce millions of identical parts, making it impossible to customize integrated systems at a deep hardware level. To address these challenges, the research team will explore a new methodology to directly print functional nanomaterials onto non-planar, flexible surfaces with unparalleled spatial resolution in three dimensions. The manufacturing platform combines spatial atomic layer deposition with electrohydrodynamic-jet printing, and incorporates in situ process monitoring and control. The research spans disciplines from molecular control of surface chemistry, to modeling coupled electro-chemo-mechanical processes that occur during printing on a curved or non-planar surface, to characterizing the impact of geometric tolerances on component performance. The additive nanomanufacturing platform enables integration of multiple functions including power, sensing, and logic into a smart contact lens that can interface with sensitive regions of the human body to monitor chemical/electrochemical changes at the cellular level. A fundamental understanding of the physical, chemical, thermal, and transport phenomena that guide the precision and accuracy of the manufacturing process will be the focus of the research, which will unveil the underlying scientific challenges to printing integrated systems at the nanoscale.

在当今计划报废的经济中，大多数消费电子产品只能在软件层面进行定制。相比之下，对于世界上绝大多数人来说，专用于用户的硬件超出了经济能力。因此，21 世纪的关键制造挑战之一是可持续、节能且经济高效的可定制生产，为每个人提供个性化的系统。这种需求在医疗领域尤其迫切，其中个性化健康监测需要根据个体独特的生理成分和几何形状定制的集成系统。该可扩展纳米制造（SNM）研究项目探索直接打印具有纳米级特征的三维集成系统所需的表面化学和物理过程，以及监控和确保打印材料和结构的质量控制的策略。这些技术可用于实现智能隐形眼镜等三维定制系统，通过将可检测体内化学变化的传感器与无线通信和向用户传输数据的电源相集成，从而实现连续和非侵入性健康监测的范式转变。这项研究结合了多个学科，包括纳米制造、建模和模拟、过程控制、系统集成和原位表征。这项工作的社会影响是通过公共教育研讨会、推广计划和关于先进纳米制造的新大学课程来实现的。当前的纳米制造研究主要集中在大批量、高通量技术上，以生产数百万个相同的零件，从而无法在深度硬件级别定制集成系统。为了应对这些挑战，研究团队将探索一种新方法，以无与伦比的三维空间分辨率将功能纳米材料直接打印到非平面柔性表面上。该制造平台将空间原子层沉积与电流体动力喷射印刷相结合，并结合了原位过程监测和控制。该研究跨越多个学科，从表面化学的分子控制，到对弯曲或非平面表面上打印过程中发生的耦合电化学机械过程进行建模，再到表征几何公差对组件性能的影响。增材纳米制造平台能够将包括电源、传感和逻辑在内的多种功能集成到智能隐形眼镜中，该隐形眼镜可以与人体的敏感区域连接，以监测细胞水平的化学/电化学变化。对指导制造过程精度和准确度的物理、化学、热和传输现象的基本理解将成为研究的重点，这将揭示纳米级打印集成系统的潜在科学挑战。

项目成果

期刊论文数量（17）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Subtractive patterning: High-resolution electrohydrodynamic jet printing with solvents

DOI：
10.1063/5.0021038
发表时间：
2020-09
期刊：
Applied Physics Letters
影响因子：
4
作者：
Nazanin Farjam;Tae H. Cho;N. Dasgupta;K. Barton
通讯作者：
Nazanin Farjam;Tae H. Cho;N. Dasgupta;K. Barton

A High-Fidelity Modeling Framework for Near-Field Electrohydrodynamic Jet Printing

DOI：
10.1016/j.ifacol.2021.11.218
发表时间：
2021
期刊：
IFAC-PapersOnLine
影响因子：
0
作者：
Nazanin Farjam;Isaac A. Spiegel;K. Barton
通讯作者：
Nazanin Farjam;Isaac A. Spiegel;K. Barton

Inkjet-defined site-selective (IDSS) growth for controllable production of in-plane and out-of-plane MoS 2 device arrays

喷墨定义的位点选择性 (IDSS) 生长，用于平面内和平面外 MoS 2 器件阵列的可控生产

DOI：
10.1039/d0nr04012f
发表时间：
2020
期刊：
Nanoscale
影响因子：
6.7
作者：
Ryu, Byunghoon;Yoon, Jeong Seop;Kazyak, Eric;Chen, Kuan-Hung;Park, Younggeun;Dasgupta, Neil P.;Liang, Xiaogan
通讯作者：
Liang, Xiaogan

Robustness of Passivated ALD Zinc Tin Oxide TFTs to Aging and Bias Stress