Workshop: International collaboration to advance biomanufacturing; September 7-8, 2017; Brussels, Belgium

研讨会：国际合作推进生物制造；

• 批准号: 1749786
• 负责人: William Bentley
• 金额: $ 4.98万
• 依托单位: University of Maryland, College Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2018-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1749786&HistoricalAwards=false
• 关键词: Workshop; International; collaboration; advance; biomanufacturing

Industrial biotechnology and biomanufacturing have the potential to benefit from advances in basic research and technology such as synthetic biology, cell free synthesis and nanomanufacturing. However, leveraging advances in basic science such that they have an economic impact has been slower in the area of biomanufacturing than in some other manufacturing areas. This is in part due to the challenges of engineering biology, where processes such as evolution and adaptation ensure the survival of species in their native environment, but hinder the development of robust, reproducible processes within bioreactors. The workshop will bring together leaders in the field from the US and Europe to address these challenges. The results of the workshop will be disseminated broadly. In addition, this meeting will provide the foundation for international collaborations between researchers in the US and Europe in the area of biomanufacturing.In order to address the challenges associated with translating advances in synthetic biology, cell free synthesis, nanomanufacturing and other areas of basic science into advances in biomanufacturing, this international workshop will be convened, with joint support from the National Science Foundation and the European Commission. The workshop will bring together leaders in the field from both sides of the Atlantic to: (1) Explore and identify areas of joint interests, needs, and opportunities associated with the translation of basic research advances in areas such as synthetic biology, cell free synthesis and nanomanufacturing (the engineering of biology) into advances in biomanufacturing and industrial biotechnology such that they have economic impact; (2) Identify research questions that could address translational potential of new technologies; (3) Explore the educational needs to ensure a well-trained and responsible workforce in the area; and (4) Assess the need for collaboration on issues such as standards and repositories, and cyberinfrastructure, as well ethical and societal concerns on an international scale.

工业生物技术和生物制造有潜力受益于合成生物学、无细胞合成和纳米制造等基础研究和技术的进步。 然而，生物制造领域利用基础科学进步产生经济影响的速度慢于其他一些制造领域。 这在一定程度上是由于工程生物学的挑战，其中进化和适应等过程确保了物种在其原生环境中的生存，但阻碍了生物反应器内稳健、可重复过程的发展。 该研讨会将汇集美国和欧洲领域的领导者来应对这些挑战。 研讨会的成果将得到广泛传播。 此外，本次会议将为美国和欧洲研究人员在生物制造领域的国际合作奠定基础。为了应对将合成生物学、无细胞合成、纳米制造和其他基础科学领域的进展转化为生物制造进展所面临的挑战，本次国际研讨会将在美国国家科学基金会和欧盟委员会的共同支持下召开。 该研讨会将汇集大西洋两岸该领域的领导者，以：（1）探索和确定与将合成生物学、无细胞合成和纳米制造（生物学工程）等领域的基础研究进展转化为生物制造和工业生物技术进展以产生经济影响相关的共同兴趣、需求和机会领域； (2) 确定可以解决新技术转化潜力的研究问题； (3) 探索教育需求，确保该地区拥有训练有素、负责任的劳动力； (4) 评估在标准和存储库、网络基础设施以及国际范围内的道德和社会问题等问题上开展合作的必要性。