Patricia Levy Zusman International Workshop on Neuroregeneration (Zusman Workshop)

项目摘要/摘要 R13是通过与神经刺激和神经可塑性领域的研究人员讨论而产生的 在休斯顿卫理公会研究院(HMRI)。2017年，我们举办了R13资助的试点研讨会， 结合神经刺激研究和对神经可塑性的分子理解的新见解 和再生。研讨会得到了与会者的强烈和积极的响应，并对进一步 工作协作的催化剂。因此，在2019年，我们促进了关系发展和交叉 通过新成立的闪电战会议(即在2019年研讨会上设立的会议)为与会者提供机会 合作团队竞争两笔5000美元的迷你赠款，以支持彼此机构的往返旅行。 2021年，我们由R13资助的研讨会由于新冠肺炎实现了100%的虚拟；然而，这并没有减少 研讨会的影响。有80多名与会者，形成了许多新的合作，并构思了项目。 鉴于绝大多数的积极反馈，我们将主办第四届帕特里夏·利维·祖斯曼国际研讨会 关于神经再生(祖斯曼研讨会)，2023年3月7日至10日。它将重点放在电子产品的交叉口 活动性、脑连接学和分子神经可塑性。我们的具体目标是：1)形成新的想法 填补生理学和功能性脑刺激技术之间的空白，以及分子和 细胞对固有神经元可塑性的理解；2)将有前途的受训者纳入全体会议；以及3) 确保受训人员参与与教职员工的实质性讨论和互动。2023年研讨会 将在HMRI举行，HMRI是德克萨斯医疗中心(TMC；一个独一无二的医疗和研究中心)的一部分 它促进了跨机构的合作、创造力和创新)，并在德克萨斯州休斯顿(美国 美国最具多样性的城市)。祖斯曼研讨会的一个关键方面是积极纳入和参与 受训人员，特别是妇女和代表性不足的少数群体。我们将通过旅行鼓励他们参与 奖学金以及在TMC内的积极推广和招聘。此外，研讨会还试图促进 研究生和博士后实习生的声音。因此，它将包括实习生海报会议以及 研修生口头陈述会议(由旅游获奖者提供)。进一步，以目标为导向的突破 由高级/早期调查人员和选定的受训人员领导的会议将促进讨论和促进交叉 培训和参与者之间的协作。总的来说，这个工作坊有别于传统的生理学。 会议和专门的神经再生会议以几种方式。它是：1)高度关注差距 在分子再生和电生理/刺激之间，2)临床医生和 实验者目前在人类治疗中解决问题，以及3)专注于交叉的建立 研究生、研究生和临床研究员的培训和专业知识发展。2023年祖斯曼研讨会 将激发创新协作并激励新的多学科团队开发创新、跨学科的 调节受损神经系统表现的方法、技术和治疗。

Project Summary/Abstract This R13 originated through discussions with investigators in the fields of neurostimulation and neuroplasticity at the Houston Methodist Research Institute (HMRI). In 2017, we held an R13-funded pilot workshop that combined research in neural stimulation with new insight into the molecular understanding of neural plasticity and regeneration. The workshop received a strong, positive response by participants and interest in further catalysts of working collaboration. Thus, in 2019, we fostered relationship development and crossover opportunities among attendees via a blitz session wherein newly formed (i.e., established at the 2019 Workshop) collaborative teams competed for two $5K mini grants that supported travel to and from each other’s institutions. In 2021, our R13-funded workshop went 100% virtual due to COVID-19; however, this did not diminish the Workshop’s impact. With over eighty attendees, many new collaborations were forged, and projects conceived. Given the overwhelmingly positive feedback, we will host the 4th Patricia Levy Zusman International Workshop on Neuroregeneration (Zusman Workshop) on March 7th-10th, 2023. It will focus on the intersection of electrical activity, brain connectomics and molecular neural plasticity. Our specific aims are to: 1) formulate new ideas to fill the gap between physiology and functional-based brain stimulation technologies and the molecular and cellular understanding of innate neuronal plasticity; 2) integrate promising trainees into plenary sessions; and 3) ensure trainees participate in substantial discussions and interactions with faculty members. The 2023 Workshop will be held at HMRI, which is part of the Texas Medical Center (TMC; a one-of-a-kind medical and research hub that fosters cross-institutional collaboration, creativity, and innovation) and is in Houston Texas (one of the United States’ most diverse cities). A key aspect of the Zusman Workshop is the active inclusion and participation of trainees, particularly women and under-represented minorities. We will encourage their participation via travel scholarships and active promotion and recruitment throughout the TMC. Also, the Workshop seeks to promote the voices of graduate and postdoctoral trainees. As such, it will include a trainee poster session as well as a session dedicated to trainee oral presentations (given by travel awardees). Further, goal-oriented breakout sessions, led by senior/early-stage investigators and selected trainees, will foster discussion and promote cross- training and collaboration among participants. Overall, this workshop is distinct from established physiology conferences and dedicated neural regeneration conferences in several ways. It is: 1) highly focused on the gap between molecular regeneration and electrophysiology/stimulation, 2) concept driven by clinicians and experimentalists currently problem solving in human therapy, and 3) focused on the establishment of cross training and expertise development in graduate, post-graduate, and clinical fellows. The 2023 Zusman Workshop will ignite innovative collaborations and spur novel multidisciplinary teams to develop innovative, transdisciplinary methods, technologies, and treatments to modulate performance in the damaged nervous system.