Collaborative Research: Multiscale Characterization and Dynamics Modeling of Stomatal Function in Plants

合作研究:植物气孔功能的多尺度表征和动力学建模

基本信息

  • 批准号:
    1852184
  • 负责人:
  • 金额:
    $ 23.78万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-07-01 至 2023-12-31
  • 项目状态:
    已结题

项目摘要

This grant will support research that will improve our understanding of the functions of stomata, the micro-size pores in plant leaf surfaces. As the gatekeeper of carbon dioxide and water vapor exchange between plants and their surrounding environment, stomata are not only crucial to the health of the individual plants, but also have a direct and global impact on the evolution of our entire ecosystem. However, currently our understanding of stomatal movement and function is limited by the conventional strategies that only captured static, averaged, and long-term macro scale behaviors of stomata. Little is known about the qualitative characteristics of stomata behavior and functions at the micro-scale, and their correlation with the underlying physiological processes of the host plant. This award supports fundamental research to create a multiscale dynamics modeling framework centered on instantaneous stomatal movement. Success of this research will create a unique, powerful tool for stomata studies and a game-changing sensing device for monitoring and controlling plants' physiological activities, opening up and enabling a wide-range of fundamental biological research (e.g., defending mechanism of plants against insect attack, plant-environment interaction) and frontier agricultural applications (e.g., optimal crop growth control, rapid genotype to phenotype transition). Thus, results from this research will benefit both the U.S. society and the economy. The multidisciplinary nature of the research across dynamic system modeling and diagnostics, micro-electro-mechanical systems, and plant biology will help to attract and broaden participations of underrepresented groups in engineering and science fields, and positively impact engineering and science education. The multiscale characterization and modeling of stomatal movement can provide the tools needed for revealing the missing links between the internal molecular dynamics and the external cellular movement involved in stomatal regulation, and for mapping and correlating biomechanical evolutions of stomata and their underneath genetic roots. However, scientific challenges are yet to be addressed to establish such a modeling framework. The research team will create a biophysics-based multiscale stomatal dynamics model that links and correlates subcellular mechanical evolutions to microscale cellular activities during stomatal movement. The modeling approach will be built upon a novel atomic force microscope technique to quantitatively map nanomechanical evolutions during single stoma movement, and one-of-a-kind miniaturized sensors to measure the water vapor and electrical potential variations caused by the stomata movements. They will also identify, evaluate, and optimize the stomatal dynamics model through experiments, by using maize and Arabidopsis thaliana as example systems.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
这笔拨款将支持研究,以提高我们对气孔功能的理解,气孔是植物叶片表面的微孔。作为植物与周围环境之间二氧化碳和水蒸气交换的守门人,气孔不仅对植物个体的健康至关重要,而且对整个生态系统的进化具有直接和全球性的影响。然而,目前我们对气孔运动和功能的理解受到传统策略的限制,这些策略只捕获了气孔静态、平均和长期宏观尺度的行为。在微观尺度上,对气孔行为和功能的定性特征及其与寄主植物潜在生理过程的关系知之甚少。该奖项支持基础研究,以创建以瞬时气孔运动为中心的多尺度动力学建模框架。这项研究的成功将为气孔研究提供一个独特而强大的工具,并为监测和控制植物的生理活动提供一个改变游戏规则的传感装置,开辟和实现广泛的基础生物学研究(如植物对昆虫攻击的防御机制,植物与环境的相互作用)和前沿农业应用(如作物最佳生长控制,基因型到表型的快速转变)。因此,这项研究的结果将有利于美国社会和经济。跨动态系统建模和诊断、微机电系统和植物生物学的多学科研究将有助于吸引和扩大工程和科学领域中代表性不足的群体的参与,并对工程和科学教育产生积极影响。气孔运动的多尺度表征和建模可以为揭示参与气孔调节的内部分子动力学和外部细胞运动之间缺失的联系提供必要的工具,并为绘制和关联气孔及其遗传根源的生物力学进化提供必要的工具。然而,建立这样一个建模框架的科学挑战还有待解决。研究小组将建立一个基于生物物理学的多尺度气孔动力学模型,将亚细胞力学进化与气孔运动过程中的微尺度细胞活动联系起来。建模方法将建立在一种新的原子力显微镜技术上,用于定量绘制单个气孔运动过程中的纳米力学演化,以及一种独一无二的小型化传感器,用于测量气孔运动引起的水蒸气和电势变化。他们还将通过实验识别、评估和优化气孔动力学模型,以玉米和拟南芥为例系统。该奖项反映了美国国家科学基金会的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A new high-frequency photoacoustic sensing probe using silicon acoustic delay lines
使用硅声延迟线的新型高频光声传感探头
Integration of microlenses on surface-micromachined optical ultrasound transducer array to improve detection sensitivity for parallel data readout
将微透镜集成在表面微机械光学超声换能器阵列上,以提高并行数据读出的检测灵敏度
  • DOI:
    10.1364/ol.476774
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    3.6
  • 作者:
    Yan, Zhiyu;Zou, Jun
  • 通讯作者:
    Zou, Jun
Large-scale 2D Surface-Micromachined Optical Ultrasound Transducer (SMOUT) array for 3D computed tomography
用于 3D 计算机断层扫描的大型 2D 表面微机械光学超声换能器 (SMOUT) 阵列
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Jun Zou其他文献

A Discrete Weighted Helmholtz Decomposition and Its Application
离散加权亥姆霍兹分解及其应用
  • DOI:
  • 发表时间:
    2013
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Qiya Hu;Shi Shu;Jun Zou
  • 通讯作者:
    Jun Zou
Volatile Ejection in Jet Manner and its Influence on Combustion of Isolated Coal Particles
喷射方式挥发分喷出及其对孤立煤粒燃烧的影响
  • DOI:
    10.1007/s12217-022-09981-0
  • 发表时间:
    2022-08
  • 期刊:
  • 影响因子:
    1.8
  • 作者:
    Wantao Yang;Yang Zhang;Bing Liu;Jun Zou;Hai Zhang;Junfu Lyu
  • 通讯作者:
    Junfu Lyu
High performance of near-infrared emission for S-band amplifier from Tm3þ-doped bismuth glass incorporated with Ag nanoparticles
掺有银纳米颗粒的 Tm3-掺杂铋玻璃的 S 波段放大器的高性能近红外发射
  • DOI:
    10.1016/j.jlumin.2020.117313
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    3.6
  • 作者:
    Shaohua Meng;Guoying Zhao;Jingshan Hou;Yufeng Liu;Yanyan Guo;Yongzheng Fang;Yan Zhou;Jun Zou
  • 通讯作者:
    Jun Zou
Characterization and immune function of the interferon-β promoter stimulator-1 in the barbel chub, Squaliobarbus curriculus
触须鲢、Squaliobarbus 课程中干扰素-β 启动子刺激物 1 的特征和免疫功能
  • DOI:
    10.1016/j.dci.2019.103571
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    Xin Zhao;Tiaoyi Xiao;Shengzhen Jin;Jing'an Wang;Junya Wang;Hong Luo;Rui Li;Tong Sun;Jun Zou;Yaoguo Li
  • 通讯作者:
    Yaoguo Li
Fourier-transform spectrometer chip covering visible band on silica planar waveguide
覆盖二氧化硅平面波导可见光波段的傅里叶变换光谱仪芯片
  • DOI:
    10.1016/j.optcom.2019.124599
  • 发表时间:
    2020-02
  • 期刊:
  • 影响因子:
    2.4
  • 作者:
    Xiao Ma;Jun Zou;Qiongchan Shao;Mingyu Li;Jian-Jun He
  • 通讯作者:
    Jian-Jun He

Jun Zou的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Jun Zou', 18)}}的其他基金

Large-Scale Optical Ultrasound Transducer Arrays for High-Speed and High-Resolution 3D Acoustic Tomography
用于高速、高分辨率 3D 声学断层扫描的大型光学超声换能器阵列
  • 批准号:
    2330199
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Fast Spectrally-Encoded Photoacoustic Microscopy for Multi-Parameter Bioenergetic Characterization of Heterogeneous Cancer Cells
合作研究:快速光谱编码光声显微镜用于异质癌细胞的多参数生物能表征
  • 批准号:
    2036134
  • 财政年份:
    2021
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: High Resolution Acoustic Manipulation of Single Cells with Integrated MEMS based Phased Arrays
合作研究:利用集成 MEMS 相控阵对单细胞进行高分辨率声学操控
  • 批准号:
    1809710
  • 财政年份:
    2018
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
EAGER: MEMS Co-Steered Optical and Acoustic Dual Modal Communication and Ranging Devices for Underwater Vehicles
EAGER:用于水下航行器的 MEMS 协同引导光学和声学双模通信和测距设备
  • 批准号:
    1748161
  • 财政年份:
    2017
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research/IDBR: High-Throughput Measurement of Oxygen Consumption Rates of Single Cells Using Wide-Field Optical-Resolution Photoacoustic Microscopy
合作研究/IDBR:使用宽视场光学分辨率光声显微镜高通量测量单细胞的耗氧率
  • 批准号:
    1255921
  • 财政年份:
    2013
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Continuing Grant
MEMS-Switched Acoustic Delay-Lines Microsystems for Advanced Ultrasonic Imaging Applications
用于高级超声成像应用的 MEMS 开关声学延迟线微系统
  • 批准号:
    1131758
  • 财政年份:
    2011
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Development of leucocyte cell lines for immunological research in teleost fish
用于硬骨鱼免疫学研究的白细胞系的开发
  • 批准号:
    G0800725/1
  • 财政年份:
    2009
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Research Grant

相似国自然基金

Research on Quantum Field Theory without a Lagrangian Description
  • 批准号:
    24ZR1403900
  • 批准年份:
    2024
  • 资助金额:
    0.0 万元
  • 项目类别:
    省市级项目
Cell Research
  • 批准号:
    31224802
  • 批准年份:
    2012
  • 资助金额:
    24.0 万元
  • 项目类别:
    专项基金项目
Cell Research
  • 批准号:
    31024804
  • 批准年份:
    2010
  • 资助金额:
    24.0 万元
  • 项目类别:
    专项基金项目
Cell Research (细胞研究)
  • 批准号:
    30824808
  • 批准年份:
    2008
  • 资助金额:
    24.0 万元
  • 项目类别:
    专项基金项目
Research on the Rapid Growth Mechanism of KDP Crystal
  • 批准号:
    10774081
  • 批准年份:
    2007
  • 资助金额:
    45.0 万元
  • 项目类别:
    面上项目

相似海外基金

Collaborative Research: Multiscale study of oscillating flow and multiphase heat transfer in porous media
合作研究:多孔介质中振荡流和多相传热的多尺度研究
  • 批准号:
    2414527
  • 财政年份:
    2024
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Multiscale Analysis and Simulation of Biofilm Mechanics
合作研究:生物膜力学的多尺度分析与模拟
  • 批准号:
    2313746
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Continuing Grant
Collaborative Research: Understanding Acoustoplasticity through Multiscale Computational and In-Situ, Time-Resolved Experimental Approach
合作研究:通过多尺度计算和原位时间分辨实验方法了解声塑性
  • 批准号:
    2148678
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: GEO OSE Track 2: Building a multiscale community-led ecosystem for crustal geology through the integration of Macrostrat and StraboSpot
合作研究:GEO OSE 第 2 轨道:通过 Macrostrat 和 StraboSpot 的集成构建多尺度社区主导的地壳地质生态系统
  • 批准号:
    2324580
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Understanding Acoustoplasticity through Multiscale Computational and In-Situ, Time-Resolved Experimental Approach
合作研究:通过多尺度计算和原位时间分辨实验方法了解声塑性
  • 批准号:
    2148646
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Multiscale Cardiomyocyte Mechano-Adaptation
合作研究:多尺度心肌细胞机械适应
  • 批准号:
    2230435
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Understanding Acoustoplasticity through Multiscale Computational and In-Situ, Time-Resolved Experimental Approach
合作研究:通过多尺度计算和原位时间分辨实验方法了解声塑性
  • 批准号:
    2328533
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Data-Driven Variational Multiscale Reduced Order Models for Biomedical and Engineering Applications
协作研究:用于生物医学和工程应用的数据驱动的变分多尺度降阶模型
  • 批准号:
    2345048
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Multiscale Mechanics of Adsorption-Deformation Coupling in Soft Nanoporous Materials
合作研究:软纳米多孔材料吸附变形耦合的多尺度力学
  • 批准号:
    2331017
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Standard Grant
Collaborative Research: Revealing Strengthening and Toughening Mechanisms in Coconut Endocarp through Integrated Multiscale Modeling and Characterization
合作研究:通过综合多尺度建模和表征揭示椰子内果皮的强化和增韧机制
  • 批准号:
    2316676
  • 财政年份:
    2023
  • 资助金额:
    $ 23.78万
  • 项目类别:
    Continuing Grant
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了