The mechanisms of Galectin3-induced stem cell dysfunction and the effects of anti-galectin3 therapy

Galectin3诱导干细胞功能障碍的机制及抗Galectin3治疗的效果

• 批准号: 19H03378
• 负责人: IMAMURA Takeshi
• 金额: $ 11.07万
• 依托单位: Tottori University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19H03378/
• 关键词: 幹細胞機能; galectin-3; 糖尿病; 細胞分化; インスリン抵抗性; Galectin-3; 糖尿病合併症; 幹細胞; 幹細胞障害; galectn-3

项目成果

Aldehyde dehydrogenase 2 polymorphism is an important gene for insulin resistance in Japanese patients with type 2 diabetes.

• DOI: 10.1016/j.metop.2023.100242
• 发表时间: 2023-06
• 期刊: Metabolism open
• 作者: Okura, Tsuyoshi;Nakamura, Risa;Anno, Mari;Ito, Yuichi;Kitao, Sonoko;Endo, Satomi;Taneda, Natsuka;Matsumoto, Kazuhisa;Shoji, Kyoko;Okura, Hiroko;Matsuzawa, Kazuhiko;Izawa, Shoichiro;Ueta, Etsuko;Kato, Masahiko;Imamura, Takeshi;Taniguchi, Shin-ichi;Yamamoto, Kazuhiro
• 通讯作者: Yamamoto, Kazuhiro

The sodium-glucose cotransporter 2 inhibitor ipragliflozin improves liver function and insulin resistance in Japanese patients with type 2 diabetes.

• DOI: 10.1038/s41598-022-05704-y
• 发表时间: 2022-02-03
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Okura T;Fujioka Y;Nakamura R;Kitao S;Ito Y;Anno M;Matsumoto K;Shoji K;Matsuzawa K;Izawa S;Okura H;Ueta E;Kato M;Imamura T;Taniguchi SI;Yamamoto K
• 通讯作者: Yamamoto K

Involvement of microRNA-133a-3p with the conversion of muscle fiber type in human skeletal myogenesis.

microRNA-133a-3p 参与人类骨骼肌发生中肌纤维类型的转换。

• 发表时间: 2020
• 作者: Yuhang Zhou;Yoshinori Ichihara;Hirotaka Iwasaki;Agung Kumawan Priyono;Tatsuya Sawano;Keiko Nagata;Jun-ichiro Miake;Hidetoshi Sakurai;Takeshi Imamura
• 通讯作者: Takeshi Imamura

Dipeptidyl peptidase 4 inhibitor improves insulin resistance in Japanese patients with type 2 diabetes: a single-arm study, a brief report.

• DOI: 10.1186/s13098-022-00850-9
• 发表时间: 2022-06-07
• 期刊: Diabetology & metabolic syndrome
• 影响因子: 4.8

鳥取大学医学部薬理学・薬物療法学 代謝研究

鸟取大学医学部，药理与药物治疗，代谢研究