Development of advanced fluorescent imaging systems for the study of bone remodeling
Development of advanced fluorescent imaging systems for the study of bone remodeling
批准号:
23390368
负责人:
IMAMURA Takeshi
金额:
$12.06万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-01 至 2014-03-31
中文摘要
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英文摘要
To clarify the molecular mechanisms of coupling between bone formation and resorption during bone remodeling, we tried to establish intravital fluorescent imaging system by which cell behavior, cell differentiation and apoptosis of osteoblasts and osteoclasts can be examined in vivo. In the present study, we established in vivo fluorescent imaging modality and generated several transgenic mice for imaging of osteoblasts and osteoclasts. Using CatK-tdTomato-Tg mouse, we could visualize osteoclast in vitro and in vivo.
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发表时间:
2011
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发表时间:
2013
期刊:
Cell Struct Funct
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Nanba D
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发表时间:
2012
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发表时间:
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2011
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批准号:19H03378
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.07万
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财政年份:2019
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负责人:IMAMURA Takeshi
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Microscale processes in the Venus atmosphere revealed by radio occultation
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批准号:24540482
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2012
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Effects of insulin resistance-related factors on the stem cell functions in vivo.
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批准号:23390056
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Development of advanced in vivo EMT imaging system and its application for the study of cancer metastasis
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批准号:23650600
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Sturm und Drang in the history of European culture
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批准号:22520328
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Study of TGFβ signaling during angiogenesis in bone metastasis sites by using in vivo optical imaging
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批准号:20390407
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资助金额:$12.31万
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Improvements of radio occultations of lunar and planetary atmospheres
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批准号:20740289
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财政年份:2005
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Screening of novel signal transducers for BMP using DNA affinity purification
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批准号:15591611
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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Screening and characterization of BMP-specific R-Smads binding proteins
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海外基金