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Examination of signaling pathway specific to oral mucosa wound healing.- Difference between oral mucosa and epidermis -

Examination of signaling pathway specific to oral mucosa wound healing.- Difference between oral mucosa and epidermis -
检查口腔粘膜伤口愈合特有的信号通路。-口腔粘膜和表皮的区别-
批准号：
23659857
负责人：
MAEDA Takeyasu
金额：
$2.33万
依托单位：
Niigata University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Challenging Exploratory Research
财政年份：
2011
资助国家：
日本
项目状态：
已结题
起止时间：
2011 至 2012
来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23659857/
关键词：
ケラチノサイトPI3K/AktシグナリングPTEN創傷治癒モデル細胞運動能口腔粘膜皮膚

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中文摘要
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英文摘要
Oral mucosa heals faster than does skin, and scar formation during the wound healing in oral mucosa is also less than that in skin. We attempted to explore these differences between oral keratinocytes and epidermal keratinocytes in vitro by intrinsic cellular, biological characteristics. PI3kinase signaling pathway was activated by using a pharmacological means. Using a scratch assay (in vitro wound healing assay), cell motility and protein expressions related to PI3kinase were examined. Those reagents used in this study did not induce any significant differences.
期刊论文(1)
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科研奖励(0)
会议论文
Intraoral grafting of tissue-engineered human oral mucosa.
DOI： 10.11607/jomi.te11
发表时间： 2013-09
期刊： The International journal of oral & maxillofacial implants
影响因子： --
作者： [Izumi K, Neiva RF, Feinberg SE]
通讯作者： Feinberg SE
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