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Elucidation of functional significance of caveola in periodontal mechanoreceptor

Elucidation of functional significance of caveola in periodontal mechanoreceptor
阐明牙周机械感受器小凹的功能意义
批准号:
20390464
负责人:
MAEDA Takeyasu
金额:
$12.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
The Ruffini endings, a primary mechanoreceptor in the periodontal ligament, well-develop caveolae in their cell membrane. The present study examined the functional significance of caveolae in the periodontal Ruffini endings. The caveolae were consisted of caveolin-1 with diverse functions. A unique immuno-localization pattern of caveolin-1 and Ca^<2+>-pump suggested caveolae is involved in the quick elimination of intracellular Ca^<2+> which influx into the axon terminals in mechanotransduction.
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Immunolocalization of caveolin-1 and Ca^<2+>-ATPase in the periodontal Ruffini endings.
牙周Ruffini末端中caveolin-1和Ca^2-ATP酶的免疫定位。
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [A. Suzuki, et al.]
通讯作者: et al.
DOI: 10.1016/j.neulet.2010.11.023
发表时间: 2011-01-20
期刊: NEUROSCIENCE LETTERS
影响因子: 2.5
作者: [Rahman, Farhana, Harada, Fumiko, Maeda, Takeyasu]
通讯作者: Maeda, Takeyasu
Dental innervation
牙齿神经支配
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Obitsu S, Hironori NA, Hasegawa A, Nakahama K, Morita I, Nishigaki N, Hayashi, Masuda T, Kannagi M., T.Maeda]
通讯作者: T.Maeda
Behavioral and histological observations of sensory impairment caused by tight ligation of the trigeminal nerve in mice.
紧密结扎三叉神经引起小鼠感觉障碍的行为和组织学观察。
DOI: --
发表时间: 2009
期刊: J.Neuroscience Methods
影响因子: --
作者: [Seino, Maeda, et al.]
通讯作者: et al.
Examination of signaling pathway specific to oral mucosa wound healing.- Difference between oral mucosa and epidermis -
  • 批准号:
    23659857
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.33万
  • 财政年份:
    2011
  • 负责人:
    MAEDA Takeyasu
  • 依托单位:
Roles of new ion channel involved in the regeneration/development of the periodontal Ruffini endings
  • 批准号:
    23390418
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $12.06万
  • 财政年份:
    2011
  • 负责人:
    MAEDA Takeyasu
  • 依托单位:
Asurvey of new factors which involve in development and regeneration process of the periodontal Ruffini endings
  • 批准号:
    18390488
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.01万
  • 财政年份:
    2006
  • 负责人:
    MAEDA Takeyasu
  • 依托单位:
Involvement of neurotrophins in development/regeneration of the periodontal Ruffini endings-An analysis using NT-4/5 KO mice
  • 批准号:
    16390522
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $9.22万
  • 财政年份:
    2004
  • 负责人:
    MAEDA Takeyasu
  • 依托单位:
海外基金