Elucidation of functional significance of caveola in periodontal mechanoreceptor
Elucidation of functional significance of caveola in periodontal mechanoreceptor
批准号:
20390464
负责人:
MAEDA Takeyasu
金额:
$12.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
The Ruffini endings, a primary mechanoreceptor in the periodontal ligament, well-develop caveolae in their cell membrane. The present study examined the functional significance of caveolae in the periodontal Ruffini endings. The caveolae were consisted of caveolin-1 with diverse functions. A unique immuno-localization pattern of caveolin-1 and Ca^<2+>-pump suggested caveolae is involved in the quick elimination of intracellular Ca^<2+> which influx into the axon terminals in mechanotransduction.
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Immunolocalization of caveolin-1 and Ca^<2+>-ATPase in the periodontal Ruffini endings.
牙周Ruffini末端中caveolin-1和Ca^2-ATP酶的免疫定位。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[A. Suzuki, et al.]
通讯作者:
et al.
DOI:
10.1016/j.neulet.2010.11.023
发表时间:
2011-01-20
期刊:
NEUROSCIENCE LETTERS
影响因子:
2.5
作者:
[Rahman, Farhana, Harada, Fumiko, Maeda, Takeyasu]
通讯作者:
Maeda, Takeyasu
Dental innervation
牙齿神经支配
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Obitsu S, Hironori NA, Hasegawa A, Nakahama K, Morita I, Nishigaki N, Hayashi, Masuda T, Kannagi M., T.Maeda]
通讯作者:
T.Maeda
Behavioral and histological observations of sensory impairment caused by tight ligation of the trigeminal nerve in mice.
紧密结扎三叉神经引起小鼠感觉障碍的行为和组织学观察。
DOI:
--
发表时间:
2009
期刊:
J.Neuroscience Methods
影响因子:
--
作者:
[Seino, Maeda, et al.]
通讯作者:
et al.
口腔解剖学
口腔解剖学
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Tsuchiya T, Nakahama K, Asakawa Y, Maemura T, Tanaka M, Takeda S, Morita M, Morita I, 前田健康]
通讯作者:
前田健康
Examination of signaling pathway specific to oral mucosa wound healing.- Difference between oral mucosa and epidermis -
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批准号:23659857
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2011
-
负责人:MAEDA Takeyasu
-
依托单位:
Roles of new ion channel involved in the regeneration/development of the periodontal Ruffini endings
-
批准号:23390418
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.06万
-
财政年份:2011
-
负责人:MAEDA Takeyasu
-
依托单位:
Asurvey of new factors which involve in development and regeneration process of the periodontal Ruffini endings
-
批准号:18390488
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.01万
-
财政年份:2006
-
负责人:MAEDA Takeyasu
-
依托单位:
Involvement of neurotrophins in development/regeneration of the periodontal Ruffini endings-An analysis using NT-4/5 KO mice
-
批准号:16390522
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.22万
-
财政年份:2004
-
负责人:MAEDA Takeyasu
-
依托单位:
THE INVOLVEMENT OF BRAIN DERIBED NEUROTROPHIC FACTOR (BDNF) IN DEVELOPMENT<REGENERATION AND MAINTENACE OF THE PERIODONTAL RUFFINI ENDINGS-A STUDY USING BDNF KNOCKOUT MICE-
-
批准号:14370580
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.02万
-
财政年份:2002
-
负责人:MAEDA Takeyasu
-
依托单位:
An attempt to promote formation of neural network on dental implants
-
批准号:12557152
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.86万
-
财政年份:2000
-
负责人:MAEDA Takeyasu
-
依托单位:
A STUDY OF DEVELOPMENT/REGENERATION PROCESSES OF THE PERIODONTAL NERVES, WITH SPECIAL REFERENCE TO THE ROLE OF NEUROTROPHINS/NEUROTROPHIN RECEPTORS.
-
批准号:12470382
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.69万
-
财政年份:2000
-
负责人:MAEDA Takeyasu
-
依托单位:
Immunocytochemical and Neurobiological study on Periodontal Nerve Fibers : A Developmental Approach and Experimental Model
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批准号:08457478
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.54万
-
财政年份:1996
-
负责人:MAEDA Takeyasu
-
依托单位:
Morphological approach to the clucidation of recognition of recognition mechanism of periodontal sensation: Immunohistochemical and electron microscopic study.
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批准号:03454421
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.22万
-
财政年份:1991
-
负责人:MAEDA Takeyasu
-
依托单位:
Immunohistochemical and Electron Microscopic Study on the Somatosensory Receptive System in Orofacial Region
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批准号:63440069
-
项目类别:Grant-in-Aid for General Scientific Research (A)
-
资助金额:$18.37万
-
财政年份:1988
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负责人:MAEDA Takeyasu
-
依托单位:
海外基金