The Role of Amyloid Protein Precursor in Mammalian Copper Transport
The Role of Amyloid Protein Precursor in Mammalian Copper Transport
批准号:
DP0664068
负责人:
Prof Ashley Bush
金额:
$32.17万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2006
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2006-01-01 至 2008-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The knowledge gained from this investigation will help us to develop new medicines for the treatment of debilitating and ever more prevalent age-related neurodegenerative diseases and will help us to illuminate the role of metals in the ageing process itself. Apart from the obvious economic and social benefits in extending the productive lifetime of its citizens, the outcomes of this project have clear commercial applications. We anticipate that there will be patents that will ensue from the programme, which will be licensed to Australian interests, and contribute to the national revenue in the biotechnology and pharmaceutical sector.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The impact of copper on protein turnover
-
批准号:DP230101031
-
项目类别:Discovery Projects
-
资助金额:$42.14万
-
财政年份:2023
-
负责人:Prof Ashley Bush
-
依托单位:
Molecular study of copper-promoted ubiquitination
-
批准号:DP190102573
-
项目类别:Discovery Projects
-
资助金额:$29.49万
-
财政年份:2019
-
负责人:Prof Ashley Bush
-
依托单位:
Development of therapeutic copper delivery agents for Menkes disease
-
批准号:nhmrc : 1113593
-
项目类别:Development Grants
-
资助金额:$44.66万
-
财政年份:2016
-
负责人:Prof Ashley Bush
-
依托单位:
Brain metal neurochemistry: mechanism-driven drug discovery for neurodegeneration
-
批准号:nhmrc : 1103703
-
项目类别:Research Fellowships
-
资助金额:$58.74万
-
财政年份:2016
-
负责人:Prof Ashley Bush
-
依托单位:
The role of copper in the early ubiquitination pathway
-
批准号:DP160100325
-
项目类别:Discovery Projects
-
资助金额:$24.43万
-
财政年份:2016
-
负责人:Prof Ashley Bush
-
依托单位:
Brain metal neurochemistry: mechanism-driven drug discovery for neurodegeneration
-
批准号:nhmrc : GNT1103703
-
项目类别:Research Fellowships
-
资助金额:$85.2万
-
财政年份:2016
-
负责人:Prof Ashley Bush
-
依托单位:
Development of therapeutic copper delivery agents for Menkes disease
-
批准号:nhmrc : GNT1113593
-
项目类别:Development Grants
-
资助金额:$65.15万
-
财政年份:2016
-
负责人:Prof Ashley Bush
-
依托单位:
Iron accumulation in the nematode C.elegans: a model of ageing
-
批准号:DP130100357
-
项目类别:Discovery Projects
-
资助金额:$27.05万
-
财政年份:2013
-
负责人:Prof Ashley Bush
-
依托单位:
Australia Fellowship
-
批准号:nhmrc : 1037234
-
项目类别:Research Fellowships
-
资助金额:$266.72万
-
财政年份:2011
-
负责人:Prof Ashley Bush
-
依托单位:
Biological Metals in Neurodegeneration
-
批准号:nhmrc : 1002222
-
项目类别:NHMRC Research Fellowships
-
资助金额:$5.3万
-
财政年份:2011
-
负责人:Prof Ashley Bush
-
依托单位:
Neural Copper Homeostasis: the role of the Alzheimer Amyloid-beta Precursor Protein
-
批准号:DP0985963
-
项目类别:Discovery Projects
-
资助金额:$22.84万
-
财政年份:2009
-
负责人:Prof Ashley Bush
-
依托单位:
The Role of Metals in the Biology of the Ageing Brain
-
批准号:FF0458331
-
项目类别:Federation Fellowships
-
资助金额:$107.08万
-
财政年份:2004
-
负责人:Prof Ashley Bush
-
依托单位:
Novel therapies for alzheimer's disease based on a-beta-metal interactions
-
批准号:nhmrc : 170201
-
项目类别:NHMRC Research Fellowships
-
资助金额:$26.69万
-
财政年份:2001
-
负责人:Prof Ashley Bush
-
依托单位:
Alzheimer's disease amyloid: a corrupted antioxidant?
-
批准号:nhmrc : 981724
-
项目类别:NHMRC Project Grants
-
资助金额:$9.54万
-
财政年份:1998
-
负责人:Prof Ashley Bush
-
依托单位:
国内基金
海外基金
登录
查看更多内容
基于聚金属氧酸盐对Amyloid蛋白的定点化学修饰及其在阿尔茨海默症治疗中的应用
-
批准号:22077118
-
项目类别:面上项目
-
资助金额:63.0万元
-
批准年份:2020
-
负责人:高楠
-
依托单位:
基于S1P通路探究Amyloid-β在干性年龄相关性黄斑变性中的作用
-
批准号:81870666
-
项目类别:面上项目
-
资助金额:57.0万元
-
批准年份:2018
-
负责人:王海燕
-
依托单位:
Amyloid-beta-PirB 相互作用介导小胶质细胞表型和功能变化参与AD进展的机制研究
-
批准号:81601123
-
项目类别:青年科学基金项目
-
资助金额:17.0万元
-
批准年份:2016
-
负责人:都瑾
-
依托单位:
Beta-amyloid寡聚体特有的抗原表位多肽疫苗的研究
-
批准号:30971012
-
项目类别:面上项目
-
资助金额:35.0万元
-
批准年份:2009
-
负责人:刘瑞田
-
依托单位:
抗阿兹海默病Beta-Amyloid寡聚物单链可变区抗体的筛选及其动物试验
-
批准号:30570622
-
项目类别:面上项目
-
资助金额:30.0万元
-
批准年份:2005
-
负责人:刘瑞田
-
依托单位: