Implantable module-based microchip networks

基于可植入模块的微芯片网络

• 批准号: 401023906
• 负责人: Professor Dr.-Ing. Maurits Ortmanns
• 金额: --
• 依托单位: Institut für Mikroelektronik (Mikro)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2018
• 资助国家: 德国
• 起止时间: 2017-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/401023906?language=en
• 关键词: Implantable; module; based; microchip; networks

The project NeuroBus deals with the realization of an implantable network of miniaturized microchips (µASICs) as neuronal interface. Various Gamma ASICs with different functions are designed as self-sufficient modules that can be freely combined in variable combinations. The individual modules are hermetically encapsulated and assembled on polyimide to form application-specific networks. The aim of the project is to study the material science and electronic fundamentals to achieve increased biostability and biocompatibility of the novel implant concept. A significant miniaturization of the ASICs, the volume reduction of the applied hermetic encapsulation and the embedding in a highly flexible polymer substrate lead us to expect a higher biological tolerability. The absence of DC voltage, the adapted adhesion promoters between the different components and the direct encapsulation of the ASICs with a thin metal film are further key aspects of the study in order to maintain an unequalled long-term stability. The conducted research work will find methods to create modular and scalable implants that can be personalized and which form the basis for a large number of other modules and thus applications in biomedical applications.

NeuroBus项目致力于实现微型微芯片（µ ASIC）作为神经元接口的可植入网络。具有不同功能的各种Gamma ASIC被设计为自给自足的模块，可以自由地以可变组合进行组合。各个模块均密封封装并组装在聚酰亚胺上，以形成特定应用的网络。该项目的目的是研究材料科学和电子基础，以提高新型植入物概念的生物稳定性和生物相容性。 ASIC的显著小型化、所应用的密封封装的体积减小以及嵌入高度柔性的聚合物基底中使我们期望更高的生物耐受性。没有直流电压，不同组件之间的适配粘合促进剂以及用薄金属膜直接封装ASIC是研究的其他关键方面，以保持无与伦比的长期稳定性。进行的研究工作将找到创建模块化和可扩展植入物的方法，这些植入物可以个性化，并形成大量其他模块的基础，从而在生物医学应用中应用。