Pathogenesis of Alzheimer's disease: Dissecting synaptosomal dysfunction in transgenic animal models

阿尔茨海默病的发病机制：剖析转基因动物模型中的突触体功能障碍

• 批准号: LP0669785
• 负责人: Prof Jürgen Götz
• 金额: $ 11.09万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-12-18 至 2008-09-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0669785
• 关键词: Pathogenesis; Alzheimer; disease; Dissecting; synaptosomal

There is no cure for Alzheimer's disease (AD). This project will dissect pathogenic mechanisms, identify new drug targets, and develop treatment strategies, all of which will be patented and eventually lead to a decrease in health costs in Australia. This research clearly falls under the national research priority of promoting and maintaining good health. Our findings are expected to benefit patients in addition to those suffering from AD, as pathocascades and pathogenic mechanisms are shared between a range of neurodegenerative disorders.

阿尔茨海默病（AD）是一种常见的慢性病。该项目将剖析致病机制，确定新的药物靶点，并制定治疗策略，所有这些都将获得专利，并最终导致澳大利亚医疗成本的下降。这项研究显然福尔斯属于促进和保持良好健康的国家研究重点。我们的研究结果预计将有利于患者除了那些患有AD，作为pathocascades和致病机制之间的一系列神经退行性疾病共享。