课题基金 / 基金详情

Studies on the mechanism of antibody production of carp in a myxosporean infection

Studies on the mechanism of antibody production of carp in a myxosporean infection
鲤鱼粘孢子虫感染产生抗体机制的研究
批准号:
04660197
负责人:
OGAWA Kazuo
金额:
$1.28万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1992
资助国家:
日本
项目状态:
已结题
起止时间:
1992 至 1993

项目摘要

项目成果

OGAWA Kazuo的其他基金

相似基金

相关文献

中文摘要
翻译
Artus粘球线虫在鲤鱼骨骼肌内形成假性包囊。一些假囊显示出异常生长,寄主组织对寄生虫的包膜不完全,导致假囊在孢子发生完成之前破裂。在孢子形成完成或非典型假囊破裂后,宿主反应开始。在一些自然感染的鲤鱼体内检测到与超声孢子反应的抗体,而另一些鱼虽然有抗体,但没有检测到感染的迹象。这种抗体在注射了寄生虫发育阶段的鲤鱼或注射了牛血清白蛋白的声波孢子中产生,但在注射完整或声波孢子的鲤鱼中不产生抗体。注射实验结果表明:1)发育阶段对鲤鱼具有抗原性;2)孢子失去抗原性;超声处理的孢子是半抗原,抗体可以与之反应。在间接荧光抗体技术中,抗原阳性的血清与寄生虫的发育阶段发生反应,但不与孢子发生反应。有可能这种抗体是在发育过程中显示异常生长的年轻假囊暴露在宿主免疫系统中时产生的。在疫苗接种试验中,注射超声孢子的鲤鱼没有表现出任何抵抗Artus感染的免疫效果。
英文摘要
Myxobolus artus formed pseudocysts in the skeletal muscle of carp. Some pseudocysts showed abnormal growth, imperfect encapsulation of the parasite by the host tissue, resulting in rupture of pseudocysts before completion of sporogenesis. After spore formation was complete or atypical pseudocysts ruptured, host reaction was initiated. Spores were phagocytosed and either transported to macrophage centers in the visceral organs or discharged from the host through the skin and intestine.The antibody which reacted with sonicated spores was detected in some naturally infected carp, while some other fish had no detectable sign of infection though they had the antibody. The antibody was produced in carp injected either with developing stages of the parasite or sonicated spores with bovine serum albumin, but not in carp injected either with intact or sonicated spores. The results of the injection experiments suggest that 1) developing stages have antigenicity to carp and 2) spores have lost it ; sonicated spores are haptens, with which the antibody can react. In an indirect fluorescent antibody technique, sera positive for the antigen reacted with developing stages of the parasite, but not with the spore. It is plausible that the antibody was produced when young pseudocysts, which showed abnormal growth ruptured during development, were exposed to the host immune system. In vaccination trials, carp injected with sonicated spores did not show any immutity agaist M.artus infection.
期刊论文(12)
专著(0)
科研奖励(0)
会议论文
T.Furuta, K.Ogawa and H.Wakabayashi: "Humoral immune response of carp Cyprinus carpio to Myxobolus artus (Myxozoa : Myxobolidae) infection" J.Fish Biol.43. 441-450 (1993)
T.Furuta、K.Okawa 和 H.Wakabayashi:“鲤鱼 Cyprinus carpio 对 Myxobolus artus(Myxozoa:Myxobolidae)感染的体液免疫反应”J.Fish Biol.43。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
T.Furuta,K.Ogawa and H.Wakabayashi: "Humoral immune response of carp Cyprinus carpio to Myxobolus artus(Myxozoa:Myxobolidal)infection" Journal of Fish Biology. 43. 441-450 (1993)
T.Furuta,K.Okawa 和 H.Wakabayashi:“鲤鱼 Cyprinus carpio 对 Myxobolus artus(Myxozoa:Myxobolidal)感染的体液免疫反应”鱼类生物学杂志。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
K.OGAWA: "Histological studies on the host responnse to Myxobolus artus Akhmerou,1960(Myxozoa:Myxobolidae) infection in the skeletal muscle of carp,Cyprinus carpio" Journal of Fish Biology. 41. 363-371 (1992)
K.OGAWA:“鲤鱼骨骼肌中宿主对 Myxobolus artus Akhmerou,1960(Myxozoa:Myxobolidae)感染反应的组织学研究”鱼类生物学杂志。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
K.Ogawa, K.P.Delgahapitiya, T.Furuta and H.Wakabayashi: "Histological studies on the host response to Myxobolus artus Akhmerov, 1960 (Myxozoa : Myxobolidae) infection in the skeletal muscle of carp, Cyprinus carpio L." J.Fish Biol.41. 363-371 (1992)
K.Okawa、K.P.Delgahapitiya、T.Furuta 和 H.Wakabayashi:“鲤鱼骨骼肌中宿主对 Myxobolus artus Akhmerov(粘虫纲:粘虫科)感染的反应的组织学研究。”
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
6
    Propagation mechanism of financial crisis and portfolio behavior of financial institutions: Comparative studies of Japan, Eu and USA
    • 批准号:
      22330068
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $8.07万
    • 财政年份:
      2010
    • 负责人:
      OGAWA Kazuo
    • 依托单位:
    Basic studies on the control of blood fluke infection of Pacific bluefin tuna
    An Empirical Study on the Relationship between Flow-of-Funds and the Real Economy : A General Equilibrium Approach to the Japanese Economy in the 1990s
    • 批准号:
      19330044
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $7.24万
    • 财政年份:
      2007
    • 负责人:
      OGAWA Kazuo
    • 依托单位:
    A Theoretical and Empirical Study on Structural Change in Flow-of-Funds of the Japanese Economy in the 1990s
    • 批准号:
      16330038
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $4.74万
    • 财政年份:
      2004
    • 负责人:
      OGAWA Kazuo
    • 依托单位:
    海外基金