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Follow-up studies on protective effects of breast feeding against rotavirus infection in infants.

母乳喂养对婴儿轮状病毒感染保护作用的随访研究。

基本信息

批准号：
04670335
负责人：
SODA Kenji
金额：
$ 0.96万
依托单位：
Yokohama City University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1992
资助国家：
日本
起止时间：
1992 至 1993
项目状态：
已结题

项目摘要

乳児嘔吐下痢症に対する母乳哺育の予防効果を明らかにするために、神奈川県AK病院の産婦及びその出生児について、1)母体血清と初乳中のロタウイルス(HRV)抗体保有率調査(検体採取:1987年7月〜1990年8月),2)出生児の乳児期栄養法と本下痢症罹患に関する質問票調査(1993年),を実施した。成績を以下に要約する。1.母体血清のHRV抗体陽性率は92%で,殆どの母親が抗体を保有していたが,25歳未満では87.5%,25〜30歳未満93.7%,30〜35歳未満96.2%,35歳以上100%で,年齢の増加とともに抗体陽性率は上昇していた。出産の概往歴別の平均抗体価は,初産婦群(74.7GEU)に比べ,経産婦群(88.1GEU)が高く,抗体陽性率も初産婦群(90%)に比べ,経産婦群(97%)は有意(P<0.01)に高かった。初乳の出産経験の有無別の抗体価分布も母体血清の成績と同様で,経産婦群は抗体価の高いことが示された。出産間隔年数が2〜3年の経産婦群では,母体血清の平均抗体価は初産婦群に比べて高かったが,4年以上の経産婦群では初産婦群とほぼ同じ平均抗体価であった。2.質問票の有効回収率は447通(回収率53%)で,対象児数は470人であった。乳児期における育児栄養法は,母乳栄養が38.3%,混合栄養54.7%,人工栄養7%であった。母乳哺育割合は,第1子31.2%、第2子41.7%、第3子以降47.8%と,出産順位によって異なっていた。乳児嘔吐下痢症の罹患児数は47人(罹患率10%)で,非罹患児群の母乳哺育率(39.2%)に比べて,罹患児群は29.8%と低かった。また,1歳未満の罹患児群では人工乳栄養児が多く,混合栄養でも母乳の哺育期間は比較的短期であった。1歳未満での乳児嘔吐下痢症の罹患率は,母乳栄養群が1%,混合栄養群が1.5%であったのに比べて、人工栄養群では3%と高かった。

Preventive effect of breast vomiting and dysentery by breast feeding, Kanagawa Prefecture AK The hospital's maternity and birth control system, 1) Maternal serum and colostrum control system (HR V) Antibody retention rate survey (body collection: July 1987~August 1990), 2) Questionnaire survey on the incidence of dysentery during the birth period and the breastfeeding period (1993), を実した. The results are below and I am making an appointment. 1. The positive rate of HRV antibody in maternal serum is 92%, and the maternal antibody is retained in the mother's serum, and the rate is 87.5% when she is 25 years old, 25 to 30 years old. 93.7% are under 30 years old, 96.2% are under 30 to 35 years old, and 100% are over 35 years old. The antibody positive rate is also increasing among those over 35 years old. The average antibody level by childbirth is higher among primiparous women (74.7GEU) and higher than among first-time mothers (88.1GEU)く, the antibody positive rate was higher among primiparous women (90%) than among first-time mothers (97%) (P<0.01). The results of colostrum production are related to whether there are any differences in the distribution of antibodies and the distribution of maternal serum. The number of years between childbirth is 2 to 3 years for the group of postpartum women, and the average maternal serum antibody level is the ratio for the group of primiparous women.て高かったが, primiparous women group and primiparous women over 4 years old have the same average antibody 価であった. 2. The effective recovery rate of question tickets was 447 (recovery rate 53%), and the number of responses was 470. The following are the methods of raising babies during the lactation period: 38.3% are breastfed, 54.7% are mixed, and 7% are artificial. Breastfeeding is divided into 31.2% for the first child, 41.7% for the second child, and 47.8% for the third child and onward. The order of delivery is the same. The number of patients with breast vomiting and dysentery was 47 (attack rate 10%), the breast-feeding rate among non-suffering patients (39.2%) was lower than that of patients with breast vomiting and dysentery, and the rate among patients with breast cancer was 29.8%.また, 1-year-old who suffers from ⅐ group では artificial milk 栄児が多く, mixed 栄愄でも breast milk の feeding period is a comparative short-term であった. The incidence rate of dysentery is 1% for infants under 1 year old, 1% for breast-fed feeding groups, 1.5% for mixed feeding groups, and 3% for artificial feeding groups.