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Biosynthesis investigations of an antifungal peptide

Biosynthesis investigations of an antifungal peptide
抗真菌肽的生物合成研究
批准号:
446001085
负责人:
Professor Dr. Roderich D. Süßmuth
金额:
$0.0万
依托单位国家:
德国
项目类别:
Research Grants
财政年份:
--
资助国家:
德国
项目状态:
未结题
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中文摘要
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英文摘要
The gene cluster of a non-ribosomally synthesized peptide from a bacterium of the phylum proteobacteria is investigated by gene inactivation mutagenesis and in-vitro reconstitution of the biosynthesis. Additionally, a synthetic approach to the peptide will be elaborated, which will concomitantly provide access to enzyme substrates. With the investigation of the gene cluster we pursue to obtain insights into a new type of non-ribosomal peptide synthesis as well as preliminary insights into structure-activity-relations.
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biosynthesis of the Avionins, a new class of lantibiotics
  • 批准号:
    385052459
  • 项目类别:
    Research Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2017
  • 负责人:
    Professor Dr. Roderich D. Süßmuth
  • 依托单位:
Ribosomal peptide secondary metabolites from fungi
  • 批准号:
    317347381
  • 项目类别:
    Research Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2016
  • 负责人:
    Professor Dr. Roderich D. Süßmuth
  • 依托单位:
Interdisciplinary studies on non-ribosonmally synthesised secondary metabolites from Paenibacillus larvae
Deciphering small molecules as virulence factors by the bacterial sugarcane pathogen Xanthomonas albilineans
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