A Cohort Study of Higher Brain Function and Motor-Kinesthetic Function in Middle and Old Age People

为了研究健康中老年人的认知和运动-动觉功能之间的关系，我们参加了名古屋大学医学院和藤田医疗福利大学进行了23年的队列研究。我们开发了名古屋大学认知评估组合（NU-CAB）作为认知心理学的研究小组，并评估了认知功能（基本上是记忆力、注意力和语言能力）的调查。根据四年来收集的数据，发现以下结果：1）.正常健康人与前额叶皮层相关的认知能力从50岁左右开始衰退。2）.有所谓的罕见-75岁以上的精英幸存者，他们保持适当的认知和运动动觉功能水平。3）认知功能和运动动觉功能之间存在一定的关系。动觉功能表明前额叶皮层和小脑-小脑连接之间有很强的联系。4）认知功能和社会心理习惯之间有一定的关系，5）认知功能与休闲活动参与等生活方式有一定的关系。

To examine the relationship between cognitive and motor-kinesthetic function in healthy middle and old people, we participated in the cohort study, which has been conducted for 23 years by Nagoya University Medical School and Fujita Medical Welfare University. We developed the Nagoya University Cognitive Assessment Battery (NU-CAB) as a research group of cognitive psychology and assessed cognitive function (basically, memory, attention and verbal abilities) of 450 to 650 people every year for four years.Based on the data collected for four years, the followings findings were revealed ;1).Cognitive abilities that related to prefrontal cortex deteriorate from age around 50 years old in normal healthy people.2).There are so-called rare-elite survivors who are above 75 years old and they are maintaining proper level of cognitive and motor-kinesthetic function.3).There are certain relationships between cognitive function and motor-kinesthetic function that suggests strong relation between prefrontal cortex and cerebro-cerebeller connection.4).There are certain relationships between cognitive function and socio-psychological habits such as drinking, smoking and physical exercise.5).There are certain relationships between cognitive function and living style such as participation of leisure activities.