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Experimental approach to sperm chromosome screening

Experimental approach to sperm chromosome screening
精子染色体筛查的实验方法
批准号:
23890013
负责人:
WATANABE Hiroyuki
金额:
$2.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
To produce offspring from pre-analyzed sperm, sperm DNA was replicated using androgenic embryos. Sister blastomeres from androgenic 2-cell embryos were individually fused to MIT oocytes to analyze sperm chromosomes and to produce offspring with known male chromosome constitutions. Also, Calyculin A facilitated the procedure in chromosome analysis of blastomere. These results demonstrated that sperm chromosome screening was successfully established.
期刊论文(8)
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会议论文
Production of mouse offspring derived from pre-analyzed paternal genome : Experimental approach to sperm genetic screening (SGS)
从预先分析的父本基因组中产生小鼠后代:精子遗传筛查(SGS)的实验方法
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Hiroyuki Watanabe, Ryuzo Yanagimachi, Hiroyuki Taten]
通讯作者: Hiroyuki Taten
精子の受精前遺伝学的診断法への実験的アプローチ
精子受精前遗传学诊断的实验方法
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [渡部 浩之, 日下部 博一, 森 英紀, 柳町 隆造, 立野 裕幸]
通讯作者: 立野 裕幸
Excessive pre-treatment of mouse spermatozoa with DNA non-interacting agents causes zygotic chromosomal damage、International Meeting for Evolution of Reproductive Biology and Task of Frontiers: Trajectory and Prospects of IVF
用DNA非相互作用剂过度预处理小鼠精子会导致合子染色体损伤,生殖生物学进化国际会议和前沿任务:体外受精的轨迹和前景
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [H. Watanabe, H. Suzuki, Y. Fukui, H. Tateno]
通讯作者: H. Tateno
Production of mouse offspring derived from pre-analyzed paternal genome: Experimental approach to sperm genetic screening (SGS)
从预先分析的父本基因组中产生小鼠后代:精子遗传筛查 (SGS) 的实验方法
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [H. Watanabe, R. Yanagimachi, H. Tateno]
通讯作者: H. Tateno
7
    Effect of inflammation on the fertilizability of spermatozoa exposed to gamma-rays
    Development of LMS corresponding to iterative learning type and its analysis of learning time
    • 批准号:
      15K01092
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2015
    • 负责人:
      WATANABE Hiroyuki
    • 依托单位:
    Development of novel 99mTc labeled amyloid imaging probes for diagnosis of Alzheimer's disease
    • 批准号:
      25893109
    • 项目类别:
      Grant-in-Aid for Research Activity Start-up
    • 资助金额:
      $2.33万
    • 财政年份:
      2013
    • 负责人:
      WATANABE Hiroyuki
    • 依托单位:
    Chromosomal risk of male germ cells in juvenile mice exposed to gamma-ray
    • 批准号:
      25870027
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.66万
    • 财政年份:
      2013
    • 负责人:
      WATANABE Hiroyuki
    • 依托单位:
    海外基金