Coordination Funds

协调基金

• 批准号: 456691453
• 负责人: Professorin Dr. Annette Becker
• 金额: --
• 依托单位: Arbeitsgruppe Spezielle Botanik
• 依托单位国家: 德国
• 项目类别: Research Units
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/456691453?language=en
• 关键词: Coordination; Funds

Early land plants have met the challenge of continuous range expansion, further away from water, always at risk of dehydration. Consequently, also the sexual reproduction of land plants is geared towards independency of water. Several key innovations in sexual reproduction originated in the land plant lineage, such as spores with a rigid outer surface, ovules harboring reduced female gametophytes and a multicellular embryo that is dispersed within seeds in a dehydrated state. Hence, the evolution of sexual reproduction in land plants provides stunning examples for the crucial biological concepts of ‚innovation‘ (e.g., origin of new reproductive structures such as ovules and flowers), and ‚coevolution‘ (e.g. between signalling peptides and receptors involved in fertilization). The evolutionary dynamics and molecular mechanisms underlying these processes are only poorly understood. In the Research Unit (RU) ICIPS seven independent research groups will bring together complementary expertise in plant molecular, developmental, cell and evolutionary biology, supported by a group with core expertise in computation and bioinformatics, to shed light on the molecular mechanisms that drive innovations in plant reproduction. ICIPS will target the evolution of key transcription factor families, the gene regulatory networks they are involved in as well as the communication between male and female reproductive structures. Here, we will establish the basis for comparisons of temporal and spatial ROS dynamics during the evolution of land plant sexual reproduction. We will put an emphasis on phylogeny and coevolution of non-seed plant relatives of genes that control crucial morphogenetic events in spermatophytes such as seed and flower development. We will combine state of the art methods of molecular biology, cell biology, in vivo imaging with genetically-encoded biosensors, genomics and transcriptomics, genome editing and bioinformatics in non-seed plant model systems that only recently have become fully established for such studies, such as the liverwort Marchantia, the moss Physcomitrium and the fern Ceratopteris. Further, this RU will foster the development of a community for young researchers in the field of evolutionary developmental biology in Germany, who will routinely combine approaches from molecular genetics and cell biology with smart bioinformatics and extend established and novel methods to non-seed plant model species.

早期的陆地植物面临着连续范围扩张的挑战，远离水，总是有脱水的风险。因此，土地植物的性繁殖也适合于水的独立性。有性繁殖的几项关键创新起源于土地植物谱系，例如具有刚性外表面的孢子，具有减少雌性配子体的胚珠和多细胞胚胎，该胚胎分散在脱水状态下的种子中。因此，陆地植物中有性繁殖的演变为“创新”的关键生物学概念（例如，新的复制结构的起源（例如胚珠和花朵）的起源）提供了惊人的例子，以及“协同进化”（例如，在涉及的涉及皮肤中涉及的信号肽和受体之间）。这些过程所基于的进化动力学和分子机制仅被鲜为人知。在研究单位（RU）中，七个独立研究小组将汇集植物分子，发育，细胞和进化生物学方面的互补专业知识，并得到了一个在计算和生物信息学方面具有核心专业知识的小组的支持，以揭示驱动植物生殖创新的分子机制。 ICIP将针对关键转录因子家族的演变，他们参与的基因调节网络以及男性和女性复制结构之间的通信。在这里，我们将在土地植物有性繁殖过程中比较临时和空间ROS动力学的基础。我们将重点放在基因的非种子植物亲戚的系统发育和共同进化中，这些基因控制精子和花朵发育等精子中关键的形态发生事件。 We will combine state of the art methods of molecular biology, cell biology, in vivo imaging with genetically-encoded biosensors, genomics and transcriptomics, genome editing and bioinformatics in Non-seed plant model systems that only recently have become fully established for such studies, such as the liverwort Marchantia, the moss Physcomitrium and the fern Ceratopteris.此外，这种RU将促进德国进化发展生物学领域的年轻研究人员的社区发展，他们将通常将分子遗传学和细胞生物学的方法与智能生物信息学结合起来，并将既定的方法扩展到非种子植物模型物种。