Social and health sciences fusion research for the elucidation process leading to cardiovascular disease from psychosocial factors

我们发现，新发现的心血管危险因素，如脂联素水平和C反应蛋白水平，除了与传统的危险因素有关外，还与心血管疾病的风险有关。我们还确定了心理因素与心血管疾病之间的可能机制。我们的结果表明，心理因素与心血管疾病风险之间的联系可能通过糖尿病和家庭高血压来调节。地区剥夺水平与个人社会经济条件调整后较高的心血管死亡率和发病率有关。心血管危险因素，特别是生物危险因素，按地区剥夺水平的不均衡分布是这种联系的机制。我们的结果表明，除了现有的个人公共卫生方法外，地区环境可能是一个重要的公共卫生目标。

We found that newly identified cardiovascular risk factors such as adiponectin levels and C-reactive protein levels were associated with risk of cardiovascular disease in addition to conventional risk factors.We also identified the possible mechanism of the association between psychological factors and cardiovascular diseases;our results suggested that the association between psychological factors and risk of cardiovascular diseases could be mediated through diabetes mellitus and home high blood pressure.Areal deprivation level was associated with higher cardiovascular mortality and morbidity after adjustment for individual socioeconomic conditions.Unequal distribution of cardiovascular risk factors,in particular biological risk factors,by areal deprivation level be a mechanism of the identified association.Our results suggest that areal environment could be a crucial public health target in addition to the existing individual public health approach.