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Social and health sciences fusion research for the elucidation process leading to cardiovascular disease from psychosocial factors

Social and health sciences fusion research for the elucidation process leading to cardiovascular disease from psychosocial factors
社会与健康科学融合研究从心理社会因素导致心血管疾病的过程
批准号:
22249022
负责人:
ISO Hiroyasu
金额:
$30.53万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010-04-01 至 2014-03-31

项目摘要

项目成果

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中文摘要
翻译
结果发现,除传统危险因素外,脂联素、C反应蛋白等新发现的心血管危险因素也与心血管疾病的发生有关,并初步探讨了心理因素与心血管疾病发生的可能机制;我们的研究结果表明,心理因素与心血管疾病风险之间的联系可能通过糖尿病介导,家庭高血压。在调整个人社会经济条件后,区域剥夺水平与较高的心血管死亡率和发病率相关。心血管危险因素,特别是生物危险因素,在区域剥夺水平上的不平等分布是确定的关联机制。我们的研究结果表明,除了现有的个人公共卫生方法外,区域环境可能是一个重要的公共卫生目标。
英文摘要
We found that newly identified cardiovascular risk factors such as adiponectin levels and C-reactive protein levels were associated with risk of cardiovascular disease in addition to conventional risk factors.We also identified the possible mechanism of the association between psychological factors and cardiovascular diseases;our results suggested that the association between psychological factors and risk of cardiovascular diseases could be mediated through diabetes mellitus and home high blood pressure.Areal deprivation level was associated with higher cardiovascular mortality and morbidity after adjustment for individual socioeconomic conditions.Unequal distribution of cardiovascular risk factors,in particular biological risk factors,by areal deprivation level be a mechanism of the identified association.Our results suggest that areal environment could be a crucial public health target in addition to the existing individual public health approach.
期刊论文(47)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1016/j.atherosclerosis.2013.06.013
发表时间: 2013-09-01
期刊: ATHEROSCLEROSIS
影响因子: 5.3
作者: [Ikeda, Ai, Iso, Hiroyasu, Tsugane, Shoichiro]
通讯作者: Tsugane, Shoichiro
健康の社会的決定要因:認知症
健康的社会决定因素:痴呆症
DOI: --
发表时间: 2010
期刊: 公衆衛生学雑誌
影响因子: --
作者: [白井こころ, 磯博康, 近藤克則]
通讯作者: 近藤克則
地域の教育水準と循環器疾患死亡リスク:JACC Study
地区教育水平与心血管疾病死亡风险:JACC 研究
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [本庄かおり, 磯博康, 藤野善久, 田邊直仁, 鈴木貞夫, 玉腰暁子]
通讯作者: 玉腰暁子
DOI: 10.1093/gerona/glt189
发表时间: 2014-07-01
期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
影响因子: 5.1
作者: [Fujiwara, Takeo, Kondo, Katsunori, Kawachi, Ichiro]
通讯作者: Kawachi, Ichiro
共 40 条
    The effect of insulin resistance and secretion against risk ofmetabolic syndrome and cardiovascular disease
    • 批准号:
      22659130
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $1.97万
    • 财政年份:
      2010
    • 负责人:
      ISO Hiroyasu
    • 依托单位:
    Large prospective cohort study for the pro-oxidant and antioxidant factors and atherosclerotic disease.
    • 批准号:
      19390174
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.32万
    • 财政年份:
      2007
    • 负责人:
      ISO Hiroyasu
    • 依托单位:
    A large epidemiological study on the interaction between inflammation, infection and antioxidants in the development of atherosclerosis
    Blood homoysteine, its associated factors, atheroscerosis and cardiovasular desease
    • 批准号:
      11470103
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.66万
    • 财政年份:
      1999
    • 负责人:
      ISO Hiroyasu
    • 依托单位:
    海外基金