Social and health sciences fusion research for the elucidation process leading to cardiovascular disease from psychosocial factors

社会与健康科学融合研究从心理社会因素导致心血管疾病的过程

• 批准号: 22249022
• 负责人: ISO Hiroyasu
• 金额: $ 30.53万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-22249022/
• 关键词: 循環器疾患; 社会疫学; 社会心理; 生活習慣; バイオマーカー

We found that newly identified cardiovascular risk factors such as adiponectin levels and C-reactive protein levels were associated with risk of cardiovascular disease in addition to conventional risk factors.We also identified the possible mechanism of the association between psychological factors and cardiovascular diseases;our results suggested that the association between psychological factors and risk of cardiovascular diseases could be mediated through diabetes mellitus and home high blood pressure.Areal deprivation level was associated with higher cardiovascular mortality and morbidity after adjustment for individual socioeconomic conditions.Unequal distribution of cardiovascular risk factors,in particular biological risk factors,by areal deprivation level be a mechanism of the identified association.Our results suggest that areal environment could be a crucial public health target in addition to the existing individual public health approach.

结果发现，除传统危险因素外，脂联素、C反应蛋白等新发现的心血管危险因素也与心血管疾病的发生有关，并初步探讨了心理因素与心血管疾病发生的可能机制;我们的研究结果表明，心理因素与心血管疾病风险之间的联系可能通过糖尿病介导，家庭高血压。在调整个人社会经济条件后，区域剥夺水平与较高的心血管死亡率和发病率相关。心血管危险因素，特别是生物危险因素，在区域剥夺水平上的不平等分布是确定的关联机制。我们的研究结果表明，除了现有的个人公共卫生方法外，区域环境可能是一个重要的公共卫生目标。

项目成果

The combination of Helicobacter pylori- and cytotoxin-associated gene-A seropositivity in relation to the risk of myocardial infarction in middle-aged Japanese: The Japan Public Health Center-based study

• DOI: 10.1016/j.atherosclerosis.2013.06.013
• 发表时间: 2013-09-01
• 期刊: ATHEROSCLEROSIS
• 影响因子: 5.3
• 作者: Ikeda, Ai;Iso, Hiroyasu;Tsugane, Shoichiro
• 通讯作者: Tsugane, Shoichiro

健康の社会的決定要因:認知症

健康的社会决定因素：痴呆症

• 发表时间: 2010
• 期刊: 公衆衛生学雑誌
• 作者: 白井こころ;磯博康;近藤克則
• 通讯作者: 近藤克則

地域の教育水準と循環器疾患死亡リスク:JACC Study

地区教育水平与心血管疾病死亡风险：JACC 研究

• 发表时间: 2011
• 作者: 本庄かおり;磯博康;藤野善久;田邊直仁;鈴木貞夫;玉腰暁子
• 通讯作者: 玉腰暁子

Associations of Childhood Socioeconomic Status and Adulthood Height With Functional Limitations Among Japanese Older People: Results From the JAGES 2010 Project

• DOI: 10.1093/gerona/glt189
• 发表时间: 2014-07-01
• 期刊: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
• 影响因子: 5.1
• 作者: Fujiwara, Takeo;Kondo, Katsunori;Kawachi, Ichiro
• 通讯作者: Kawachi, Ichiro

Living alone and risk of cardiovascular events following discharge after acute myocardial infarction in Japan

• DOI: 10.1016/j.jjcc.2013.04.009
• 发表时间: 2013-09-01
• 期刊: JOURNAL OF CARDIOLOGY
• 影响因子: 2.5
• 作者: Kitamura, Tetsuhisa;Sakata, Yasuhiko;Komuro, Issei
• 通讯作者: Komuro, Issei