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High resolutional MR images of cochlear nerves and functional PET of temporal lobes in patients with sensory nerve hearing loss.

High resolutional MR images of cochlear nerves and functional PET of temporal lobes in patients with sensory nerve hearing loss.
感觉神经性听力损失患者耳蜗神经的高分辨率 MR 图像和颞叶的功能 PET。
批准号:
14570837
负责人:
SATO Noriko
金额:
$1.34万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2002
资助国家:
日本
项目状态:
已结题
起止时间:
2002 至 2003

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中文摘要
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英文摘要
The new MR sequence, CISS (constructive interference with steady state), provide high resolutional images which had not been imaged before. Cochlear nerve that is responsible for auditory system can be demonstrated by MR CISS images. We examined the anatomical abnormalities of cochlear nerve in patients with auditory disturbance using MR CISS images. We examined whether there is any differences of cochlear nerve size among various diseases or between before and after treatment. At the same time, brain blood volume was also estimated on positron CT by auditory stimulations before and after treatment and examined the differences of brain blood volume between two patients' groups of improvement and non-respons by treatment.Patients with unilateral sensory neural hearing loss without neoplasms such as acoustic shwanoma were selected. High-resolutional 3D images were scanned with MR CISS sequences (effective slice thickness was 0.7mm), and cranial nerve 7th and 8th were reconstructed vertic … More al to the nerves. The size of cochlear nerve on reconstructed images was compared of right and left. In patients who was infetected by mumpus virus, the size of cochlear nerve at disease side was smaller then the contralateral side. But facial and vestibular nerves were symmetric. On the other hand, in patients with idiopathic hearing loss, which are supposed to be caused by blood flow disturbance, there were no differences of both sides.Pure sound stimulation test was examined in patients with idiopathic auditory disturbance on positron CT. The treatment was steroid and high oxygen therapy. In patients who were improved after treatment, bilateral temporal blood volume were increased compared to that before treatment. There were no blood volume differences between before and after treatment in patients who did not respond by the therapy.It is clinical asset to demonstrate anatomical and functional abnormalities that had not been detected before. We evaluate the morphological change objectively and this method is helpful to precise diagnose in patients with auditory disturbance. Less
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J Aoki: "FDG-PET for preoperative differential diagnosis between benign and malignant soft tissue masses."Skeketal Radiol. 32. 133-138 (2003)
J Aoki:“FDG-PET 用于良性和恶性软组织肿块的术前鉴别诊断。”Skeketal Radiol。
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Taketomi, A: "The effect of frequency encoding qradient upon margin depictibility and height measurements in normal adult pituitary glands"Neuroradiology 2003. (in press). (2003)
Taketomi, A:“频率编码 qradient 对正常成人垂体的边缘可描述性和高度测量的影响”Neuroradiology 2003。(出版中)。
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N Sato: "Gliomatosis cerebri evaluated by ^<18>F α-methyl tyrosine positron-emission tomography."Neuroradiology. 45. 700-707 (1993)
N Sato:“通过^ 18 F α-甲基酪氨酸正电子发射断层扫描评估脑胶质瘤病。”神经放射学45。700-707(1993)
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A Taketomi: "The effect of frequency-encoding gradient upon detectability of the margins and height measurements of normal adult pituitary gland."Neuroradiology. 46. 60-64 (2004)
A Taketomi:“频率编码梯度对正常成人垂体边缘和高度测量的可检测性的影响。”神经放射学。
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