High resolutional MR images of cochlear nerves and functional PET of temporal lobes in patients with sensory nerve hearing loss.

感觉神经性听力损失患者耳蜗神经的高分辨率 MR 图像和颞叶的功能 PET。

• 批准号: 14570837
• 负责人: SATO Noriko
• 金额: $ 1.34万
• 依托单位: Gunma University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14570837/
• 关键词: kannouseinanncyou; cochlear nerve; MR; CISS; Positron CT

The new MR sequence, CISS (constructive interference with steady state), provide high resolutional images which had not been imaged before. Cochlear nerve that is responsible for auditory system can be demonstrated by MR CISS images. We examined the anatomical abnormalities of cochlear nerve in patients with auditory disturbance using MR CISS images. We examined whether there is any differences of cochlear nerve size among various diseases or between before and after treatment. At the same time, brain blood volume was also estimated on positron CT by auditory stimulations before and after treatment and examined the differences of brain blood volume between two patients' groups of improvement and non-respons by treatment.Patients with unilateral sensory neural hearing loss without neoplasms such as acoustic shwanoma were selected. High-resolutional 3D images were scanned with MR CISS sequences (effective slice thickness was 0.7mm), and cranial nerve 7th and 8th were reconstructed vertic … More al to the nerves. The size of cochlear nerve on reconstructed images was compared of right and left. In patients who was infetected by mumpus virus, the size of cochlear nerve at disease side was smaller then the contralateral side. But facial and vestibular nerves were symmetric. On the other hand, in patients with idiopathic hearing loss, which are supposed to be caused by blood flow disturbance, there were no differences of both sides.Pure sound stimulation test was examined in patients with idiopathic auditory disturbance on positron CT. The treatment was steroid and high oxygen therapy. In patients who were improved after treatment, bilateral temporal blood volume were increased compared to that before treatment. There were no blood volume differences between before and after treatment in patients who did not respond by the therapy.It is clinical asset to demonstrate anatomical and functional abnormalities that had not been detected before. We evaluate the morphological change objectively and this method is helpful to precise diagnose in patients with auditory disturbance. Less

新的MR序列CISS（对稳态的建设性干扰）提供了以前未成像的高分辨率图像。负责听觉系统的耳蜗神经可以通过MR CISS图像来证明。我们使用MR CISS图像检查了听觉灾难患者的耳蜗神经的解剖异常。我们检查了各种疾病之间的耳蜗神经大小是否存在任何区别，或者治疗前后。同时，还通过治疗前后的听觉刺激估算了脑血容量，并检查了两名患者的改善和非响应板之间的脑血量的差异。选择了单侧感觉神经听力损失，而没有声性疾病，例如，选择了诸如声学疾病瘤的单方面感觉神经听力损失。用MR CISS序列（有效切片厚度为0.7mm）扫描高分辨率3D图像，并且颅神经7th和8th被重建了Vertic…更重要的是神经。比较了重建图像上的耳蜗神经的大小。在受肿瘤病毒影响的患者中，疾病侧的耳蜗神经的大小要小于对比度。但是面部和前庭神经是对称的。另一方面，在特发性听力损失的患者中，应该是由血流障碍引起的，双方没有差异。该治疗是立体和高氧疗法。在治疗后改善的患者中，与治疗前的双侧临时血容量相比增加了。治疗前后没有通过治疗反应的患者之间没有血量差异。这是临床资产以证明以前未曾检测到的解剖和功能异常。我们客观地评估形态变化，此方法有助于听觉灾难患者的精确诊断。较少的

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