Epidemiologic studies on environmental and host-specific factors for human cancers

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The priority area of the cancer epidemiology were formed by 4 study branches : 1) ethnoepidemiology ; analytical epidemiology ; 3) molecular epidemiology ; 4) clinical epidemiology. Furthermore, three promoting committees of large-scaled cohort study, molecular epidemiology and ATL research, supported the study programs in this area. The Japan Collaborative Cohort (JACC) study started from 1988 generated many new findings on risk and protective factors of Japanese cancer and these evidences were evaluated by seroepidemiological evidences. The committee of molecular epidemiology established a standard system for reservation of national and international human samples and effectual usage of these important materials. Furthermore its committee completed a standard manual for establishment of the Japanese Multi-institutional Collaborative Cohort (J-MICC) after deliberating all issues of ethical correspondence, standardization of questionnaire, collecting methods of blood samples, long-term reservation of human materials. The promoting committee of ATL research reviewed epidemiologic, basic and clinical studies conducted in the last 20 years and suggested several remaining and important subject. Available information obtained from this study area should be disseminated to prevent Japanese cancer, therefore, public symposia were organized twice a year in Tokyo and other cities from Hokkaido to Kyushu district. published useful information for cancer prevention Finally all information obtained from 25 planned subjects in five years were brought together into a couple of books entitled the forefront of cancer prevention" and also opened to the public by home page.