EP-DEMIOLOGICAL STUDY ONENVIRONMENTAL AND HOST-SPECIFIC FACT0RS FOR INCREASING CANCERS IN JAPAN, CHINA AND KOREA

日本、中国和韩国癌症发病率增加的环境和宿主特异性因素的流行病学研究

• 批准号: 17015052
• 负责人: TAJIMA Kazuo
• 金额: $ 88.58万
• 依托单位: Aichi Cancer Center Research Institute
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17015052/
• 关键词: 乳・大腸がん; 民族疫学; 環境・宿主交互作用; がん予防; 国際研究交流; 大腸がん; 乳がん; 危険・防御要因; 国際研究者交流; 中国:韓国; 北東アジア; 生活習慣要因; 脂肪酸分画; 遺伝子多型; 環境・宿主相互作用; リスクファクター; 症例対照研究

乳・大腸がんは日・中・韓三国で増加しつつあり、その環境・宿主要因を分子疫学的に解明し、三国における予防対策に寄与することを本研究課題の主目的と定め、平成17年度より五年計画で第二次三国共同研究を推進した。乳・大腸がんの三国における一般的増加要因を確認し、さらに、乳がんでは十分な大豆製品や葉酸の摂取が危険度を下げ、遺伝的にFGFR2の過剰発現群では肥満傾向や角経早期開始などの影響が大きいことなどを鮮明にした。

The environmental accommodation of the three countries in Japan, China and Japan is mainly due to the understanding of molecular epidemiology, the strategy of prevention and control in the three countries and the subject of this research project, and the promotion of the second joint study of the Pingcheng five-year Plan in Pingcheng. The general requirements of the three countries are to make sure that the soybean products are in critical condition, and that the FGFR2 concentration of the soybean products is very low, and the quality of the products in the three countries is very high.

项目成果

Development of a semi-quantitative food frequency questionnaire for middle-aged inhabitants in the Chaoshan area, China.

• DOI: 10.3748/wjg.v11.i26.4078
• 发表时间: 2005-07
• 期刊: World journal of gastroenterology
• 影响因子: 4.3
• 作者: Feng-Yan Song;Takezaki Toshiro;Ke Li;P. Yu;Xu-Kai Lin;He-Lin Yang;Xiao-ling Deng;Yu-qi Zhang;Lai-Wen Lv;Xingxing Huang;Tajima Kazuo

Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor pylori seropositivity, gastric atrophy and gastric cancer in Japanese.

• DOI: 10.1186/1471-230x-9-51
• 发表时间: 2009-07-09
• 期刊: BMC gastroenterology
• 影响因子: 2.4
• 作者: Hishida A;Matsuo K;Goto Y;Naito M;Wakai K;Tajima K;Hamajima N
• 通讯作者: Hamajima N

Effect of soybean on breast cancer according to receptor status: A case-control study in Japan

• DOI: 10.1002/ijc.23644
• 发表时间: 2008-10-01
• 期刊: INTERNATIONAL JOURNAL OF CANCER
• 影响因子: 6.4
• 作者: Suzuki, Takeshi;Matsuo, Keitaro;Tajima, Kazuo
• 通讯作者: Tajima, Kazuo

Relative validity of a short food frequency questionnaire for assessing nutrient intake versus three-day weighed diet records in middle-aged Japanese.

• DOI: 10.2188/jea.15.135
• 发表时间: 2005-07
• 期刊: Journal of epidemiology
• 影响因子: 4.7
• 作者: Tokudome Y;Goto C;Imaeda N;Hasegawa T;Kato R;Hirose K;Tajima K;Tokudome S
• 通讯作者: Tokudome S

ゲノム疫学の光と影.

基因组流行病学的光与影。

• 发表时间: 2008
• 作者: Matsuo;K.;Tajima K.;Tajima K;Tajima K;TajimaK;Tajima K;Tajima K;Tajima K;Tajima K;田島和雄;Tajima K.
• 通讯作者: Tajima K.