Development of a light detection system for enhanced scanning electron microscopy imaging of fully hydrated biological specimens at room temperature.
Development of a light detection system for enhanced scanning electron microscopy imaging of fully hydrated biological specimens at room temperature.
批准号:
LP0562159
负责人:
Prof Matthew Phillips
金额:
$16.04万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2006
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2006-08-14 至 2009-08-14
中文摘要
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英文摘要
This project aims to develop instrumentation and techniques to image fully hydrated cellS for prolonged periods at room temperature in an environmental scanning electron microscope. Multiple fluorescent nano-particle labels will be used to image complex cellular structure and dynamics at ultra high spatial resolution. This innovative bio-imaging technique will be facilitated by the construction of a high speed light collection system that can efficiently operate at the pressures required to stablise water within the cell. Applications for this new bio-imaging technique will also be explored.
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