Next generation of IVMFC technical development by identification of the microtubule control factor of oocyte.
Next generation of IVMFC technical development by identification of the microtubule control factor of oocyte.
批准号:
21248032
负责人:
SATO Eimei
金额:
$30.2万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
以显著提高未成熟卵母细胞体外成熟(IVM)水平作为卵母细胞体外培养体系的核心,重点研究了未成熟卵母细胞微管(缝隙连接、核膜、染色体、内质网、纺锤体、线粒体、皮质颗粒)的定位、形态和功能,并确定了控制剂。此外,还搜索了人工控制控制剂表达的化学物质。
英文摘要
Improve spectacularly of in vitro maturation (IVM) of an immature oocyte which makes the core of in vitro culture system of oocyte is aimed, it focused on localization, morphology and function of the microtubules (e.g. gap junction, nuclear membrane, chromosome, endoplasmic reticulum, spindle, mitochondria, cortical granule) of an immature oocyte, and identified the control agent. Furthermore, the chemical substance which controls expression of a control agent artificially was searched.
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DOI:
10.1016/j.rbmo.2009.10.011
发表时间:
2010-01-01
期刊:
REPRODUCTIVE BIOMEDICINE ONLINE
影响因子:
4
作者:
[Cecconi, Sandra, Rossi, Gianna, Macchiarelli, Guido]
通讯作者:
Macchiarelli, Guido
Molecular basis of follic ular growth and oocyte maturation-Use of farm animals for biology andbiomedical sience
卵泡生长和卵母细胞成熟的分子基础-农场动物在生物学和生物医学科学中的应用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Sato, E]
通讯作者:
E
DOI:
--
发表时间:
2010
期刊:
Cell.Reprogram. (in press)
影响因子:
--
作者:
[Fujita K., Sato K, 藤田貴志,野口航,寺島一郎, 佐藤英明]
通讯作者:
佐藤英明
排卵と受精、生殖卵巣学(石塚文平、鈴木秋悦編)
排卵与受精、生殖卵巢学(石冢文平、铃木昭吉编)
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hirano Y, Kaneko G, Koyama H, Ushio H, Watabe S, 佐藤英明]
通讯作者:
佐藤英明
Combination of co-culture with parthenogenetic embryo and aggregation enhances in vitro development and quality of miniature pig somatic cell nuclear transfer embryos
共培养与孤雌胚胎聚集相结合提高小型猪体细胞核移植胚胎的体外发育和质量
DOI:
--
发表时间:
2012
期刊:
Reprod.Biotechnol
影响因子:
--
作者:
[Terashita, Y., Sugimura, S., Kudo, Y., Amano, R., Sato, E]
通讯作者:
E
共 19 条
Improvement of IVM based on the elucidation of meiosis pause mechanism by uppermost stream factor identification of oocyte maturation inhibitory factor group
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批准号:23658236
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2011
-
负责人:SATO Eimei
-
依托单位:
Development of fundamental basis for embryo-biotechnology in next generation by clarifying the regulatory mechanisms of cell differentiation and apoptosis of oocytes
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批准号:16108003
-
项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$66.89万
-
财政年份:2004
-
负责人:SATO Eimei
-
依托单位:
Identification of genes and angogenic factors involving in selective growth and apoptosis of oocytes
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批准号:13460129
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.42万
-
财政年份:2001
-
负责人:SATO Eimei
-
依托单位:
Identification of biological factors involving in serial culturing technique for germ cell series
-
批准号:10306018
-
项目类别:Grant-in-Aid for Scientific Research (A).
-
资助金额:$22.78万
-
财政年份:1998
-
负责人:SATO Eimei
-
依托单位:
The production of transgenic pigs for xenotransplantation
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批准号:10556059
-
项目类别:Grant-in-Aid for Scientific Research (B).
-
资助金额:$8.06万
-
财政年份:1998
-
负责人:SATO Eimei
-
依托单位:
active substance regulating differentiation of germ lines
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批准号:08456147
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.48万
-
财政年份:1996
-
负责人:SATO Eimei
-
依托单位:
Porcine embryonic stem cells forming germ line chimeras
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批准号:07506005
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$9.92万
-
财政年份:1995
-
负责人:SATO Eimei
-
依托单位:
Regulatory mechanisms of selective growth and death of oocytes
-
批准号:06454123
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.67万
-
财政年份:1994
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负责人:SATO Eimei
-
依托单位:
Physiologically active substances regulating ovarian function
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批准号:03454098
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项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$3.78万
-
财政年份:1991
-
负责人:SATO Eimei
-
依托单位:
Improvement of meiotic competence of follicular oocytes by artificial techniques
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批准号:61560305
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1986
-
负责人:SATO Eimei
-
依托单位: