Basic Studies on Mammalian Fertilization and Implantation
Basic Studies on Mammalian Fertilization and Implantation
批准号:
21248038
负责人:
BABA Tadashi
金额:
$29.95万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012
中文摘要
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英文摘要
This study has focused on the molecular mechanisms on mammalian fertilization and implantation. On the basis of the results obtained, sperm entry into the cumulus mass may be dependent on capacitation status of sperm. The present study also proposes that fertilizing sperm complete acrosomal exocytosis in the cumulus matrix and on the oocyte zona pellucida before fusing with the oocyte. A factor that facilitates sperm/oocyte fusion has been identified in uterine and oviductal fluids. Moreover, activation of ERalpha in the ERK1/2 pathway may play an important role in embryo implantation.
期刊论文(32)
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会议论文
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DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Baba, T]
通讯作者:
T
Localization of a PSMA8-containing proteasome in mouse sperm
小鼠精子中含有 PSMA8 的蛋白酶体的定位
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Koyama, M., Koga, Y., Hyodo, H., Yamashita, M., Ogichi, K., Kanemori, Y., Sawada H., Baba, T]
通讯作者:
T
DOI:
10.1262/jrd.2011-006
发表时间:
2012-06-01
期刊:
JOURNAL OF REPRODUCTION AND DEVELOPMENT
影响因子:
1.8
作者:
[Zhou, Chong, Kang, Woojin, Baba, Tadashi]
通讯作者:
Baba, Tadashi
Functional roles of sperm hyaluronidase, HYAL5 and SPAM1
精子透明质酸酶、HYAL5 和 SPAM1 的功能作用
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kang, W., Kimura, M., Kim, E., Yamashita,M., Saigo, M., Yamazaki, T., Nakanishi, T., Kashiwabara, S., Baba, T]
通讯作者:
T
Characterization of a novel PSMA8-containing proteasome present in mouse sperm
小鼠精子中存在的新型含 PSMA8 蛋白酶体的表征
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Koga, Y., Koyama, M., Hyodo, H., Yamashita, M., Sawada, H., Baba, T]
通讯作者:
T
共 29 条
Functional Regulation of Migrating Sperm in the Mouse Oviduct
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批准号:18K06241
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2018
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负责人:BABA Tadashi
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依托单位:
Basic and Applied Studies on Regulation of Gene Expression by Small DNAs
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批准号:26650004
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2014
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依托单位:
Integrated analyses of virulence factors from Staphylococcus aureusaiming to pursue novel pathogenic mechanisms and chemotherapy based on new concept
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批准号:22590402
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2010
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负责人:BABA Tadashi
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依托单位:
Regulatory Mechanism of Sperm Function in Female Reproductive Tract
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批准号:18208029
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$23.71万
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财政年份:2006
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负责人:BABA Tadashi
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依托单位:
Molecular basis of spermatogenesis and fertilization in mammals
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批准号:15208033
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$27.96万
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财政年份:2003
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负责人:BABA Tadashi
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依托单位:
Studies on the Regulation of Fertilization and Activation of Development
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批准号:12306018
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$28.24万
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财政年份:2000
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负责人:BABA Tadashi
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依托单位:
Molecular Mechanism of Functional Regulation of Spermatiogenic Cells by Interaction with Other Somatic Cells and Eggs
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批准号:11235201
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$59.71万
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财政年份:1999
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负责人:BABA Tadashi
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依托单位:
Functional alteration of cereal starches using the genes encoding starch-synthesizing enzymes
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批准号:10556029
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$8.0万
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财政年份:1998
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负责人:BABA Tadashi
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依托单位:
Studies on Sperm Function in Fertilization
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批准号:09460154
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.32万
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财政年份:1997
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负责人:BABA Tadashi
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依托单位:
Studies on Molecular Mechanism of Starch Biosynthesis
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批准号:07660092
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:1995
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负责人:BABA Tadashi
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依托单位:
Studies on the sperm/oocyte interaction in fertilization
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批准号:07044179
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$3.07万
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财政年份:1995
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负责人:BABA Tadashi
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依托单位:
国内基金
海外基金
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