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Synthesis of stimuli-responsive star polymers for controlled drug delivery

Synthesis of stimuli-responsive star polymers for controlled drug delivery
用于控制药物输送的刺激响应星形聚合物的合成
批准号：
DP0450915
负责人：
Prof Martina Stenzel
金额：
$16.36万
依托单位：
The University of New South Wales
依托单位国家：
澳大利亚
项目类别：
Discovery Projects
财政年份：
2004
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2004-03-26 至 2007-12-31
来源：
https://dataportal.arc.gov.au/RGS/Web/Grants/DP0450915
关键词：
Synthesisstimuliresponsivestarpolymers

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中文摘要
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英文摘要
The project aims to prepare novel star polymers suitable for drug delivery via controlled radical polymerization techniques. Such star polymers can be employed to release drugs within the human body in a controlled manner over time and are thus able to target specific sites, i.e. a tumor. The release characterisitics are be influenced by the structure and the size of the star polymer, which can easily be altered via controlled radical polymerization techniques. These novel stars are expected to improve the release kinetics of the drug comparing to similar structured micelles due to their higher stability upon injection.
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