A platform for the efficient optimisation of drug delivery using cross-linked micelles and thioclick-chemistry toward better anti-cancer treatment

使用交联胶束和硫代点击化学有效优化药物输送的平台，以实现更好的抗癌治疗

• 批准号: DP110102409
• 负责人: Prof Martina Stenzel
• 金额: $ 31.67万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-04 至 2014-04-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP110102409
• 关键词: platform; efficient; optimisation; drug; delivery

The delivery of albendazole - an anti-cancer drug - will be improved by encapsulating the drug into nanoparticles. State of the art polymer chemistry will be employed to generate a versatile drug delivery system. The resulting nanoparticles will be able to better control drug delivery and to enhance cellular uptake of the drug.

阿苯达唑-一种抗癌药物-的递送将通过将药物封装到纳米颗粒中来改善。将采用最先进的聚合物化学技术来产生通用的药物递送系统。由此产生的纳米颗粒将能够更好地控制药物递送并增强药物的细胞摄取。