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Physico-chemical approach on the construction of functional denovo cell

Physico-chemical approach on the construction of functional denovo cell
功能性新生细胞构建的物理化学方法
批准号:
18GS0421
负责人:
YOSHIKAWA Kenichi
金额:
$330.64万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Creative Scientific Research
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2010

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中文摘要
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英文摘要
1) We have successfully constructed a model experimental system exhibiting robust on/off switching on genetic activity accompanied by the structural transition of a giant DNA molecule. 2) It is shown that micro-confinement causes specific phase-segregation. We demonstrated marked acceleration of gene-expression reaction in an artificial model cell. 3) We proposed a novel theoretical model to explain the emergent process of the morphology in multicellular systems.
期刊论文(141)
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会议论文
Large system in a small cell : A hypothetical pathway from a microscopic stochastic process towards robust genetic regulation
小细胞中的大系统:从微观随机过程到强大的遗传调控的假设途径
DOI: --
发表时间: 2010
期刊: Chemical Physics Letters
影响因子: 2.8
作者: [H.Nagahara, K.Yoshikawa]
通讯作者: K.Yoshikawa
ホームページ(代表者吉川研一関係)
主页(代表人:吉川健一)
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Protein-conjugated QD effectively delivered into living cells by a cationic nanogel
蛋白质缀合的量子点通过阳离子纳米凝胶有效递送到活细胞中
DOI: --
发表时间: 2008
期刊: J.Nanosci.Nanotech. 8
影响因子: --
作者: [S.Toita, U.Hasegawa, H.Koga, I.Sekiya, T.Muneta, K.Akiyoshi.]
通讯作者: K.Akiyoshi.
Survival versus collapse: Abrupt drop of excitability kills the traveling pulse, while gradual change results in adaptation
生存与崩溃:兴奋性的突然下降会扼杀行进的脉搏,而逐渐的变化会导致适应
DOI: --
发表时间: 2007
期刊: Physical Review E 76
影响因子: --
作者: [M. Tanaka, H. Nagahara, H. Kitahata, V. Krinsky, K. Agladze, K. Yoshikawa]
通讯作者: K. Yoshikawa
118
    Generation of macroscopic autonomous motion induced photon flux
    Analytic torsion and geometry of moduli spaces
    Nonlinear Dynamics of Mesoscopic Systems under Laser Irradiation
    • 批准号:
      14340115
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.41万
    • 财政年份:
      2002
    • 负责人:
      YOSHIKAWA Kenichi
    • 依托单位:
    Thermodynamics and Kinetics on the Folding Transition of Single Molecular Chain
    • 批准号:
      10206204
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas (B)
    • 资助金额:
      $14.72万
    • 财政年份:
      1998
    • 负责人:
      YOSHIKAWA Kenichi
    • 依托单位:
    海外基金