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International Epidemiologic Study on Risk Factor and Prevention for Depression / Suicide among Japanese Adolescents and Youths.

日本青少年抑郁/自杀危险因素及预防的国际流行病学研究。

基本信息

批准号：
09670377
负责人：
TAKEUCHI Kazuo
金额：
$ 1.66万
依托单位：
Gunma Prefectural College of Health Sciences
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09670377/
关键词：
Adolescents Depression Suicide International Comparison Psychiatric Epidemiology

项目摘要

The purpose of this study is to investigate the prevalence rate and risk factors on depression among Japanese adolescents. using the DSM diagnostic algorithm. With self-administered questionnaires (the DSD). and semi-structured interviews (the SC ID). two epidemiologic surveys (on school adolescents and on clinical patients) were carried out. For school adolescents (the 8th grade). 238 of the 259 subjects (91.9%) responded in the DSD questionnaires, and 164 of the 191 (85.9%) in the SOID interviews. The 16 subjects were diagnosed as Major Depressive Episode (MDE) by the DSD (the prevalence rate=6.7%), and the 17 (10.4%) by the SOID.These rates were similar to those shown in previous studies. However. the agreement of the MDE diagnosis between the two measures was not so high (kappa=163, n=157). Those in the lower categories for the diagnosis were also low, especially in 'change in appetite/weight' and in 'difficulties in concentration'. In risk assessment for the MDE positives by the DSD, with multiple logistic regression analysis, girls had higher risk than boys did (0dds Ratio=3.3). Feeling that they could not go to school, even if wished to go, was also higher risky (0R=3.1), as well as being bullied in school (0R=3.3). For outpatients in adolescent psychiatry clinic. 34 patients answered for the DSD, and the 14 of them were interviewed on the SOID.Eight patients were diagnosed as MDE by the DSD (the positive rate=23.5%), and seven (50.0%) by the SOID.The agreement on the MDE diagnosis between the two measures in outpatients were relatively higher (kappa=571, n=14) than in general school adolescents. Among the lower categories for the diagnosis, the agreement in 'change in appetite/weight' was low again, but that in 'difficulties in concentration' was quite high. Further studies on these findings will be needed with collecting much more samples on clinical patients and with investigating their medical records.

本研究的目的是调查日本青少年抑郁症的患病率及危险因素。采用DSM诊断算法。自行填写问卷（DSD）。和半结构化访谈（SC ID）。开展了两项流行病学调查（在校青少年和临床患者）。针对学校青少年（八年级）。259名受试者中有238人（91.9%）回答了DSD问卷，191名受试者中有164人（85.9%）回答了SOID访谈。16例经DSD诊断为重度抑郁发作（MDE），患病率6.7%，17例经SOID诊断为重度抑郁发作（MDE），患病率10.4%。这些比率与之前的研究结果相似。然而。两种方法诊断MDE的一致性不高（kappa=163, n=157）。那些被诊断为较低类别的人也很低，尤其是在“食欲/体重变化”和“注意力不集中”方面。在DSD对MDE阳性的风险评估中，经多元logistic回归分析，女孩的风险高于男孩（0dds Ratio=3.3）。即使自己想去上学，也觉得不能去上学的风险较高（0R=3.1），在学校被欺负的风险较高（0R=3.3）。青少年精神病学门诊病人。34例患者回答了DSD，其中14例进行了SOID访谈。DSD诊断为MDE 8例（阳性率为23.5%），SOID诊断为7例（50.0%）。门诊患者两项指标对MDE诊断的一致性（kappa=571, n=14）相对于普通学龄期青少年较高。在诊断的较低类别中，“食欲/体重变化”的一致性再次很低，但“注意力不集中”的一致性相当高。需要对这些发现进行进一步的研究，收集更多的临床患者样本并调查他们的医疗记录。